Title |
Laparoscopic drilling by diathermy or laser for ovulation induction in anovulatory polycystic ovary syndrome
|
---|---|
Published in |
Cochrane database of systematic reviews, June 2012
|
DOI | 10.1002/14651858.cd001122.pub4 |
Pubmed ID | |
Authors |
Cindy Farquhar, Julie Brown, Jane Marjoribanks |
Abstract |
Surgical ovarian wedge resection was the first established treatment for women with anovulatory polycystic ovary syndrome (PCOS) but was largely abandoned both due to the risk of postsurgical adhesions and the introduction of medical ovulation induction. However, women with PCOS who are treated with medical ovulation induction, with drugs such as gonadotrophins, often have an over-production of follicles which may result in ovarian hyperstimulation syndrome and multiple pregnancies. Moreover, gonadotrophins, though effective, are costly and time-consuming and their use requires intensive monitoring. Surgical therapy with laparoscopic ovarian 'drilling' (LOD) may avoid or reduce the need for medical ovulation induction, or may facilitate its usefulness. The procedure can be done on an outpatient basis with less trauma and fewer postoperative adhesions than with traditional surgical approaches. Many uncontrolled observational studies have claimed that ovarian drilling is followed, at least temporarily, by a high rate of spontaneous ovulation and conception, or that subsequent medical ovulation induction becomes easier. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 33% |
United States | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | <1% |
Ukraine | 1 | <1% |
Brazil | 1 | <1% |
Unknown | 231 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 29 | 12% |
Researcher | 25 | 11% |
Student > Ph. D. Student | 24 | 10% |
Student > Bachelor | 21 | 9% |
Student > Postgraduate | 20 | 9% |
Other | 54 | 23% |
Unknown | 61 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 89 | 38% |
Nursing and Health Professions | 20 | 9% |
Agricultural and Biological Sciences | 14 | 6% |
Biochemistry, Genetics and Molecular Biology | 11 | 5% |
Pharmacology, Toxicology and Pharmaceutical Science | 8 | 3% |
Other | 26 | 11% |
Unknown | 66 | 28% |