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Mood disorder with mixed, psychotic features due to vitamin b12 deficiency in an adolescent: case report

Overview of attention for article published in Child and Adolescent Psychiatry and Mental Health, June 2012
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#6 of 455)
  • High Attention Score compared to outputs of the same age (98th percentile)

Mentioned by

blogs
1 blog
twitter
55 tweeters
facebook
6 Facebook pages
googleplus
2 Google+ users

Citations

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11 Dimensions

Readers on

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76 Mendeley
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Title
Mood disorder with mixed, psychotic features due to vitamin b12 deficiency in an adolescent: case report
Published in
Child and Adolescent Psychiatry and Mental Health, June 2012
DOI 10.1186/1753-2000-6-25
Pubmed ID
Authors

Ali Evren Tufan, Rabia Bilici, Genco Usta, Ayten Erdoğan

Abstract

Vitamin B12 is one of the essential vitamins affecting various systems of the body. Reports of psychiatric disorders due to its deficiency mostly focus on middle aged and elderly patients. Here we report a case of vitamin B 12 deficiency in a 16-year old, male adolescent who presented with mixed mood disorder symptoms with psychotic features. Chief complaints were "irritability, regressive behavior, apathy, crying and truancy" which lasted for a year. Premorbid personality was unremarkable with no substance use/exposure or infections. No stressors were present. The patient was not vegetarian. Past medical history and family history was normal. Neurological examination revealed glossitis, ataxia, rigidity in both shoulders, cog-wheel rigidity in the left elbow, bilateral problems of coordination in cerebellar examination, reduced swinging of the arms and masked face. Romberg's sign was present. Laboratory evaluations were normal. Endoscopy and biopsy revealed atrophy of the gastric mucosa with Helicobacter Pylori colonization. Schilling test was suggestive of malabsorbtion. He was diagnosed with Mood disorder with Mixed, Psychotic Features due to Vitamin B12 Deficiency and risperidone 0.5 mg/day and intramuscular vitamin B12 500 mcg/day were started along with referral for treatment of Helicobacter pylori. A visit on the second week revealed no psychotic features. Romberg's sign was negative and cerebellar tests were normal. Extrapyramidal symptoms were reduced while Vitamin B12 levels were elevated. Risperidone was stopped and parenteral Vitamin B12 treatment was continued with monthly injections for 3 months. Follow-up endoscopy and biopsy at the first month demonstrated eradication of H. pylori. He was followed monthly for another 6 months and psychiatric symptoms did not recur at the time of last evaluation. Despite limitations, this case may underline the observation that mood disorders with psychotic features especially with accompanying extrapyramidal symptoms lacking a clear etiology may be rare manifestation of vitamin B12 and/or folate deficiency in children and adolescents and be potentially amenable to treatment.

Twitter Demographics

The data shown below were collected from the profiles of 55 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 76 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 76 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 13 17%
Student > Master 13 17%
Researcher 10 13%
Student > Ph. D. Student 9 12%
Student > Postgraduate 7 9%
Other 15 20%
Unknown 9 12%
Readers by discipline Count As %
Medicine and Dentistry 24 32%
Psychology 15 20%
Nursing and Health Professions 6 8%
Agricultural and Biological Sciences 5 7%
Neuroscience 3 4%
Other 10 13%
Unknown 13 17%

Attention Score in Context

This research output has an Altmetric Attention Score of 55. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 March 2020.
All research outputs
#356,777
of 14,540,762 outputs
Outputs from Child and Adolescent Psychiatry and Mental Health
#6
of 455 outputs
Outputs of similar age
#2,312
of 123,490 outputs
Outputs of similar age from Child and Adolescent Psychiatry and Mental Health
#1
of 2 outputs
Altmetric has tracked 14,540,762 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 455 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 123,490 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them