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Effect of longer-term modest salt reduction on blood pressure

Overview of attention for article published in this source, January 2004
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4 tweeters
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2 Wikipedia pages

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Title
Effect of longer-term modest salt reduction on blood pressure
Published by
John Wiley & Sons, Ltd, January 2004
DOI 10.1002/14651858.cd004937
Pubmed ID
Authors

He, Feng J, MacGregor, Graham A

Abstract

Many randomised trials assessing the effect of salt reduction on blood pressure show reduction in blood pressure in individuals with high blood pressure. However, there is controversy about the magnitude and the clinical significance of the fall in blood pressure in individuals with normal blood pressure. Several meta-analyses of randomised salt reduction trials have been published in the last few years. However, most of these included trials of very short duration (e.g. 5 days) and included trials with salt loading followed by salt deprivation (e.g. from 20 to 1 g/day) over only a few days. These short-term experiments are not appropriate to inform public health policy which is for a modest reduction in salt intake over a prolonged period of time. A meta-analysis by Hooper et al is an important attempt to look at whether advice to achieve a long-term salt reduction (i.e. more than 6 months) in randomised trials causes a fall in blood pressure. However, most trials included in this meta-analysis achieved a small reduction in salt intake; on average, salt intake was reduced by 2 g/day. It is, therefore, not surprising that this analysis showed a small fall in blood pressure, and that a dose-response to salt reduction was not demonstrable.

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Mendeley readers

The data shown below were compiled from readership statistics for 141 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 1%
United Kingdom 2 1%
Canada 1 <1%
Peru 1 <1%
Spain 1 <1%
Italy 1 <1%
Unknown 133 94%

Demographic breakdown

Readers by professional status Count As %
Student > Master 31 22%
Student > Bachelor 18 13%
Researcher 17 12%
Student > Postgraduate 16 11%
Student > Ph. D. Student 12 9%
Other 37 26%
Unknown 10 7%
Readers by discipline Count As %
Medicine and Dentistry 75 53%
Agricultural and Biological Sciences 12 9%
Nursing and Health Professions 11 8%
Social Sciences 6 4%
Pharmacology, Toxicology and Pharmaceutical Science 4 3%
Other 18 13%
Unknown 15 11%