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RNAi in the regulation of mammalian viral infections

Overview of attention for article published in BMC Biology, June 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (93rd percentile)

Mentioned by

blogs
2 blogs
twitter
11 tweeters

Citations

dimensions_citation
41 Dimensions

Readers on

mendeley
118 Mendeley
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Title
RNAi in the regulation of mammalian viral infections
Published in
BMC Biology, June 2012
DOI 10.1186/1741-7007-10-58
Pubmed ID
Authors

Kuan-Teh Jeang

Abstract

Although RNA interference (RNAi) is known to play an important part in defense against viruses of invertebrates, its contribution to mammalian anti-viral defense has been a matter of dispute. This is surprising because all components of the RNAi machinery necessary for robust RNAi-mediated restriction of viruses are conserved in mammals, and the introduction of synthetic small interfering RNAs (siRNAs) into cells efficiently silences the replication of viruses that contain siRNA complementary sequences in those cells. Here, I discuss the reasons for the dispute, and review the evidence that RNAi is a part of the physiological defense of mammalian cells against viral infections.

Twitter Demographics

The data shown below were collected from the profiles of 11 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 118 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 3%
France 2 2%
Finland 1 <1%
Brazil 1 <1%
Ghana 1 <1%
Iran, Islamic Republic of 1 <1%
Belgium 1 <1%
Japan 1 <1%
Greece 1 <1%
Other 1 <1%
Unknown 105 89%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 37 31%
Student > Master 17 14%
Researcher 16 14%
Student > Bachelor 11 9%
Professor > Associate Professor 7 6%
Other 20 17%
Unknown 10 8%
Readers by discipline Count As %
Agricultural and Biological Sciences 62 53%
Biochemistry, Genetics and Molecular Biology 20 17%
Immunology and Microbiology 9 8%
Medicine and Dentistry 7 6%
Engineering 2 2%
Other 6 5%
Unknown 12 10%

Attention Score in Context

This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 March 2020.
All research outputs
#1,104,388
of 15,892,757 outputs
Outputs from BMC Biology
#349
of 1,361 outputs
Outputs of similar age
#8,056
of 127,941 outputs
Outputs of similar age from BMC Biology
#1
of 1 outputs
Altmetric has tracked 15,892,757 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,361 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 19.6. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 127,941 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them