You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
| Title |
RNAi in the regulation of mammalian viral infections
|
|---|---|
| Published in |
BMC Biology, June 2012
|
| DOI | 10.1186/1741-7007-10-58 |
| Pubmed ID | |
| Authors |
Kuan-Teh Jeang |
| Abstract |
Although RNA interference (RNAi) is known to play an important part in defense against viruses of invertebrates, its contribution to mammalian anti-viral defense has been a matter of dispute. This is surprising because all components of the RNAi machinery necessary for robust RNAi-mediated restriction of viruses are conserved in mammals, and the introduction of synthetic small interfering RNAs (siRNAs) into cells efficiently silences the replication of viruses that contain siRNA complementary sequences in those cells. Here, I discuss the reasons for the dispute, and review the evidence that RNAi is a part of the physiological defense of mammalian cells against viral infections. |
X Demographics
The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 18% |
| United States | 1 | 9% |
| Mexico | 1 | 9% |
| France | 1 | 9% |
| Spain | 1 | 9% |
| Unknown | 5 | 45% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 55% |
| Scientists | 4 | 36% |
| Science communicators (journalists, bloggers, editors) | 1 | 9% |
Mendeley readers
The data shown below were compiled from readership statistics for 134 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 2% |
| France | 2 | 1% |
| Ghana | 1 | <1% |
| Brazil | 1 | <1% |
| Finland | 1 | <1% |
| Portugal | 1 | <1% |
| Belgium | 1 | <1% |
| Iran, Islamic Republic of | 1 | <1% |
| Greece | 1 | <1% |
| Other | 1 | <1% |
| Unknown | 121 | 90% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 37 | 28% |
| Researcher | 19 | 14% |
| Student > Master | 19 | 14% |
| Student > Bachelor | 11 | 8% |
| Professor > Associate Professor | 8 | 6% |
| Other | 20 | 15% |
| Unknown | 20 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 63 | 47% |
| Biochemistry, Genetics and Molecular Biology | 23 | 17% |
| Immunology and Microbiology | 10 | 7% |
| Medicine and Dentistry | 7 | 5% |
| Linguistics | 2 | 1% |
| Other | 8 | 6% |
| Unknown | 21 | 16% |