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Programación epigenética placentaria en restricción del crecimiento intrauterino

Overview of attention for article published in Revista chilena de pediatría, May 2016
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (58th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (62nd percentile)

Mentioned by

twitter
5 tweeters

Citations

dimensions_citation
3 Dimensions

Readers on

mendeley
72 Mendeley
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Title
Programación epigenética placentaria en restricción del crecimiento intrauterino
Published in
Revista chilena de pediatría, May 2016
DOI 10.1016/j.rchipe.2016.04.009
Pubmed ID
Authors

Paola Casanello, José A. Castro-Rodríguez, Ricardo Uauy, Bernardo J. Krause

Abstract

Intrauterine growth restriction (IUGR) is a perinatal condition affecting foetal growth, with under the 10th percentile of the weight curve expected for gestational age. This condition has been associated with higher cardiovascular and metabolic risk and post-natal obesity. There are also major changes in placental function, and particularly in a key molecule in this regulation, nitric oxide. The synthesis of nitric oxide has numerous control mechanisms and competition with arginase for their common substrate, the amino acid L-arginine. This competition is reflected in various vascular diseases and particularly in the endothelium of the umbilical vessels of babies with IUGR. Along with this, there is regulation at the epigenetic level, where methylation in specific regions of some gene promoters, such as the nitric oxide synthase, regulating their expression. It is currently of great interest to understand the mechanisms by which diseases such as IUGR may be conditioned, particularly by maternal nutritional and metabolic conditions, and epigenetic mechanisms that could eventually be modifiable, and thus a focus of interest for health interventions.

Twitter Demographics

The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Uruguay 1 1%
Unknown 71 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 19 26%
Student > Master 11 15%
Professor > Associate Professor 6 8%
Researcher 6 8%
Student > Doctoral Student 6 8%
Other 16 22%
Unknown 8 11%
Readers by discipline Count As %
Medicine and Dentistry 26 36%
Biochemistry, Genetics and Molecular Biology 12 17%
Nursing and Health Professions 8 11%
Agricultural and Biological Sciences 4 6%
Neuroscience 3 4%
Other 10 14%
Unknown 9 13%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 May 2016.
All research outputs
#6,777,293
of 12,591,254 outputs
Outputs from Revista chilena de pediatría
#51
of 396 outputs
Outputs of similar age
#106,580
of 263,992 outputs
Outputs of similar age from Revista chilena de pediatría
#5
of 16 outputs
Altmetric has tracked 12,591,254 research outputs across all sources so far. This one is in the 45th percentile – i.e., 45% of other outputs scored the same or lower than it.
So far Altmetric has tracked 396 research outputs from this source. They receive a mean Attention Score of 1.3. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 263,992 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 62% of its contemporaries.