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A Prevalência da Hipotensão Ortostática e a Distribuição da Variação Pressórica no Estudo Longitudinal da Saúde do Adulto

Overview of attention for article published in Arquivos Brasileiros de Cardiologia, June 2020
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Title
A Prevalência da Hipotensão Ortostática e a Distribuição da Variação Pressórica no Estudo Longitudinal da Saúde do Adulto
Published in
Arquivos Brasileiros de Cardiologia, June 2020
DOI 10.36660/abc.20180354
Pubmed ID
Authors

Ana Paula Costa Velten, Isabela Bensenor, Paulo Lotufo, José Geraldo Mill

Abstract

Background Orthostatic hypotension (OH) has been neglected in clinical practice, and there are no studies on its prevalence in the Brazilian population. Objective To determine the prevalence of OH and blood pressure (BP) changes after the postural change maneuver in participants of the Longitudinal Study of Adult Health. Methods In this descriptive study of baseline data (N = 14,833 adults, ages 35 - 74 years), participants remained lying down for 20 minutes and subsequently stood up actively. BP measurements were taken while the participants were supine and at 2, 3, and 5 minutes after standing. OH was defined as a reduction of ≥ 20 mmHg in systolic BP and/or a reduction of ≥ 10 mmHg in diastolic BP at 3 minutes, and its prevalence was determined with a 95% confidence interval (CI). The distribution of BP variation after the postural change maneuver was determined in a subsample (N = 8,011) obtained by removing patients with cardiovascular morbidity and/or diabetes. Results The prevalence of OH was 2.0% (95% CI: 1.8 - 2.3), increasing with age. If the criterion applied were a BP reduction during any measurement, the prevalence would increase to 4.3% (95% CI: 4.0 - 4.7). Symptoms (dizziness, scotoma, nausea, etc.) were reported by 19.7% of participants (95% CI: 15.6 - 24.6) with OH and 1.4% (95% CI: 1.2 - 1.6) of participants without OH. The -2 Z-scores of BP variation before and after the postural change maneuver in the subsample were -14.1 mmHg for systolic BP and -5.4 mmHg for diastolic BP. Conclusion Prevalence of OH varies depending on when BP is measured. Current cutoff points may underestimate the actual occurrence of OH in the population. (Arq Bras Cardiol. 2020; [online].ahead print, PP.0-0).

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Mendeley readers

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Geographical breakdown

Country Count As %
Unknown 13 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 3 23%
Student > Bachelor 3 23%
Student > Ph. D. Student 2 15%
Student > Doctoral Student 1 8%
Professor 1 8%
Other 2 15%
Unknown 1 8%
Readers by discipline Count As %
Medicine and Dentistry 3 23%
Agricultural and Biological Sciences 2 15%
Pharmacology, Toxicology and Pharmaceutical Science 1 8%
Mathematics 1 8%
Psychology 1 8%
Other 2 15%
Unknown 3 23%