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LINE-1 methylation in visceral adipose tissue of severely obese individuals is associated with metabolic syndrome status and related phenotypes.

Overview of attention for article published in Clinical Epigenetics, July 2012
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Title
LINE-1 methylation in visceral adipose tissue of severely obese individuals is associated with metabolic syndrome status and related phenotypes.
Published in
Clinical Epigenetics, July 2012
DOI 10.1186/1868-7083-4-10
Pubmed ID
Authors

Turcot, Valérie, Tchernof, André, Deshaies, Yves, Pérusse, Louis, Bélisle, Alexandre, Marceau, Simon, Biron, Simon, Lescelleur, Odette, Biertho, Laurent, Vohl, Marie-Claude

Abstract

Epigenetic mechanisms may be involved in the regulation of genes found to be differentially expressed in the visceral adipose tissue (VAT) of severely obese subjects with (MetS+) versus without (MetS-) metabolic syndrome (MetS). Long interspersed nuclear element 1 (LINE-1) elements DNA methylation levels (%meth) in blood, a marker of global DNA methylation, have recently been associated with fasting glucose, blood lipids, heart diseases and stroke.

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 1 2%
Unknown 44 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 27%
Researcher 10 22%
Student > Master 8 18%
Student > Doctoral Student 4 9%
Student > Bachelor 4 9%
Other 5 11%
Unknown 2 4%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 38%
Biochemistry, Genetics and Molecular Biology 11 24%
Medicine and Dentistry 6 13%
Computer Science 2 4%
Physics and Astronomy 1 2%
Other 3 7%
Unknown 5 11%