@jessica_l_buck 3 major mechanisms depending on anesthetic class: either top down (NMDA), bottom-up (=mimicking sleep, a2 adreno), or both (GABA). All 3 mechs impair the driving input of arousal nuclei to midline thalamic neurons and thus cortical feedbac
RT @Gozzi_Ale: The (Un)Conscious Mouse as a Model for Human Brain Functions: Key Principles of Anesthesia and Their Impact on Translational…
RT @FrontNeurosci: New Research: The (Un)Conscious Mouse as a Model for Human Brain Functions: Key Principles of Anesthesia and Their Impac…
RT @FrontNeurosci: New Research: The (Un)Conscious Mouse as a Model for Human Brain Functions: Key Principles of Anesthesia and Their Impac…