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Reduced or modified dietary fat for preventing cardiovascular disease

Overview of attention for article published in Sao Paulo Medical Journal, April 2016
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#6 of 291)
  • High Attention Score compared to outputs of the same age (94th percentile)

Mentioned by

2 news outlets
1 blog
1 policy source
9 X users
1 Wikipedia page


22 Dimensions

Readers on

267 Mendeley
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Reduced or modified dietary fat for preventing cardiovascular disease
Published in
Sao Paulo Medical Journal, April 2016
DOI 10.1590/1516-3180.20161342t1
Pubmed ID

Lee Hooper, Carolyn D. Summerbell, Rachel Thompson, Deirdre Sills, Felicia G. Roberts, Helen J. Moore, George Davey Smith


Reduction and modification of dietary fats have differing effects on cardiovascular risk factors (such as serum cholesterol), but their effects on important health outcomes are less clear. To assess the effect of reduction and/or modification of dietary fats on mortality, cardiovascular mortality, cardiovascular morbidity and individual outcomes including myocardial infarction, stroke and cancer diagnoses in randomised clinical trials of at least 6 months duration. Search methods: For this review update, the Cochrane Central Register of Controlled Trials (CENTRAL), Medline and Embase, were searched through to June 2010. References of Included studies and reviews were also checked. Trials fulfilled the following criteria: 1) randomized with appropriate control group, 2) intention to reduce or modify fat or cholesterol intake (excluding exclusively omega-3 fat interventions), 3) not multi factorial, 4) adult humans with or without cardiovascular disease, 5) intervention at least six months, 6) mortality or cardiovascular morbidity data available. Participant numbers experiencing health outcomes in each arm were extracted independently in duplicate and random effects meta-analyses, meta-regression, sub-grouping, sensitivity analyses and funnel plots were performed. This updated review suggested that reducing saturated fat by reducing and/or modifying dietary fat reduced the risk of cardiovascular events by 14% (RR 0.86, 95% CI 0.77 to 0.96, 24 comparisons, 65,508 participants of whom 7% had a cardiovascular event, I2 50%). Subgrouping suggested that this reduction in cardiovascular events was seen in studies of fat modification (not reduction - which related directly to the degree of effect on serum total and LDL cholesterol and triglycerides), of at least two years duration and in studies of men (not of women). There were no clear effects of dietary fat changes on total mortality (RR 0.98, 95% CI 0.93 to 1.04, 71,790 participants) or cardiovascular mortality (RR 0.94, 95% CI 0.85 to 1.04, 65,978 participants). This did not alter with sub-grouping or sensitivity analysis. Few studies compared reduced with modified fat diets, so direct comparison was not possible. The findings are suggestive of a small but potentially important reduction in cardiovascular risk on modification of dietary fat, but not reduction of total fat, in longer trials. Lifestyle advice to all those at risk of cardiovascular disease and to lower risk population groups, should continue to include permanent reduction of dietary saturated fat and partial replacement by unsaturates. The ideal type of unsaturated fat is unclear.

X Demographics

X Demographics

The data shown below were collected from the profiles of 9 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 267 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 <1%
Netherlands 1 <1%
Australia 1 <1%
Indonesia 1 <1%
India 1 <1%
South Africa 1 <1%
Unknown 260 97%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 52 19%
Student > Master 38 14%
Other 25 9%
Researcher 22 8%
Student > Ph. D. Student 13 5%
Other 53 20%
Unknown 64 24%
Readers by discipline Count As %
Medicine and Dentistry 70 26%
Nursing and Health Professions 41 15%
Agricultural and Biological Sciences 17 6%
Biochemistry, Genetics and Molecular Biology 13 5%
Social Sciences 8 3%
Other 43 16%
Unknown 75 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 38. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 April 2022.
All research outputs
of 24,862,067 outputs
Outputs from Sao Paulo Medical Journal
of 291 outputs
Outputs of similar age
of 306,072 outputs
Outputs of similar age from Sao Paulo Medical Journal
of 4 outputs
Altmetric has tracked 24,862,067 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 291 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 306,072 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them