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Crystal structure of the conserved domain of the DC lysosomal associated membrane protein: implications for the lysosomal glycocalyx

Overview of attention for article published in BMC Biology, January 2012
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2 tweeters

Citations

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52 Dimensions

Readers on

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74 Mendeley
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1 CiteULike
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Title
Crystal structure of the conserved domain of the DC lysosomal associated membrane protein: implications for the lysosomal glycocalyx
Published in
BMC Biology, January 2012
DOI 10.1186/1741-7007-10-62
Pubmed ID
Authors

Sonja Wilke, Joern Krausze, Konrad Büssow

Abstract

The family of lysosome-associated membrane proteins (LAMP) comprises the multifunctional, ubiquitous LAMP-1 and LAMP-2, and the cell type-specific proteins DC-LAMP (LAMP-3), BAD-LAMP (UNC-46, C20orf103) and macrosialin (CD68). LAMPs have been implicated in a multitude of cellular processes, including phagocytosis, autophagy, lipid transport and aging. LAMP-2 isoform A acts as a receptor in chaperone-mediated autophagy. LAMP-2 deficiency causes the fatal Danon disease. The abundant proteins LAMP-1 and LAMP-2 are major constituents of the glycoconjugate coat present on the inside of the lysosomal membrane, the 'lysosomal glycocalyx'. The LAMP family is characterized by a conserved domain of 150 to 200 amino acids with two disulfide bonds.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 74 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Australia 1 1%
Unknown 73 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 22 30%
Researcher 10 14%
Student > Bachelor 10 14%
Student > Master 8 11%
Student > Postgraduate 7 9%
Other 8 11%
Unknown 9 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 31 42%
Biochemistry, Genetics and Molecular Biology 18 24%
Medicine and Dentistry 4 5%
Chemistry 4 5%
Neuroscience 4 5%
Other 2 3%
Unknown 11 15%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 August 2012.
All research outputs
#9,637,407
of 12,554,200 outputs
Outputs from BMC Biology
#1,026
of 1,132 outputs
Outputs of similar age
#80,679
of 119,675 outputs
Outputs of similar age from BMC Biology
#8
of 9 outputs
Altmetric has tracked 12,554,200 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,132 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 17.7. This one is in the 6th percentile – i.e., 6% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 119,675 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 29th percentile – i.e., 29% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one.