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Evaluation of human first trimester decidual and telomerase-transformed endometrial stromal cells as model systems of in vitro decidualization

Overview of attention for article published in Reproductive Biology and Endocrinology, December 2011
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Title
Evaluation of human first trimester decidual and telomerase-transformed endometrial stromal cells as model systems of in vitro decidualization
Published in
Reproductive Biology and Endocrinology, December 2011
DOI 10.1186/1477-7827-9-155
Pubmed ID
Authors

Leila Saleh, Gerlinde R Otti, Christian Fiala, Jürgen Pollheimer, Martin Knöfler

Abstract

Decidualization, the differentiation process of maternal uterine stromal cells into secretory decidual cells, is a prerequisite for successful implantation and progression of pregnancy. For in vitro differentiation mostly primary human endometrial stromal cells (HESC) isolated from uterine samples after hysterectomy for benign gynaecological diseases are utilised. However, a continuous supply of endometrial tissue is often lacking. Hence, we analysed whether cultivated human decidual stromal cells (HDSC) prepared from first trimester pregnancy terminations may represent an alternative model system for in vitro decidualization. Moreover, based on the expression of critical marker genes these cells were compared to a previously established endometrial stromal cell line during in vitro differentiation.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Austria 1 2%
Unknown 63 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 19%
Student > Master 8 13%
Student > Doctoral Student 5 8%
Researcher 5 8%
Student > Bachelor 4 6%
Other 8 13%
Unknown 22 34%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 27%
Medicine and Dentistry 9 14%
Biochemistry, Genetics and Molecular Biology 8 13%
Engineering 2 3%
Social Sciences 2 3%
Other 2 3%
Unknown 24 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 July 2012.
All research outputs
#20,161,674
of 22,671,366 outputs
Outputs from Reproductive Biology and Endocrinology
#828
of 965 outputs
Outputs of similar age
#218,970
of 240,831 outputs
Outputs of similar age from Reproductive Biology and Endocrinology
#28
of 32 outputs
Altmetric has tracked 22,671,366 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 965 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.9. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 240,831 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 32 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.