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Skin prick testing does not reflect the presence of IgE against food allergens in adult eosinophilic esophagitis patients: a case study

Overview of attention for article published in Clinical and Molecular Allergy, November 2010
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Title
Skin prick testing does not reflect the presence of IgE against food allergens in adult eosinophilic esophagitis patients: a case study
Published in
Clinical and Molecular Allergy, November 2010
DOI 10.1186/1476-7961-8-16
Pubmed ID
Authors

Toral A Kamdar, Anne M Ditto, Paul J Bryce

Abstract

Skin prick testing is widely used to predict the presence of allergen-specific IgE. In eosinophilic esophagitis patients, who frequently exhibit polysensitization and broad reactivity upon skin prick testing, this is commonly used to aid avoidance recommendations in the clinical management of their disease. We present here the predictive value of skin prick testing for the presence of allergen-specific IgE, in 12 patients, determined by immunoblot against the allergen extracts using individual-matched serum. Our results demonstrate a high degree of predictive value for aeroallergens but a poor predictive value for food allergens. This suggests that skin prick testing likely identifies IgE reactivity towards aeroallergens in adult eosinophilic esophagitis but this is not true for foods. Consequently, IgE immunoblotting might be required for determining food avoidance in these patients.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 2 9%
Unknown 21 91%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 39%
Other 4 17%
Student > Bachelor 3 13%
Student > Master 3 13%
Student > Ph. D. Student 1 4%
Other 3 13%
Readers by discipline Count As %
Medicine and Dentistry 14 61%
Agricultural and Biological Sciences 3 13%
Immunology and Microbiology 2 9%
Computer Science 1 4%
Biochemistry, Genetics and Molecular Biology 1 4%
Other 1 4%
Unknown 1 4%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 July 2017.
All research outputs
#14,729,713
of 22,671,366 outputs
Outputs from Clinical and Molecular Allergy
#156
of 211 outputs
Outputs of similar age
#138,855
of 179,746 outputs
Outputs of similar age from Clinical and Molecular Allergy
#2
of 2 outputs
Altmetric has tracked 22,671,366 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 211 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.1. This one is in the 25th percentile – i.e., 25% of its peers scored the same or lower than it.
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