RT @florian_krammer: 101) This vaccine candidate is currently being evaluated at the 100 μg dose in phase III clinical trials in adults, in…
#半ワクチン派 若年層はコロナ感染リスクが小さいんだから投与量半分で良いんじゃない? ・1/4で発熱等の副反応少ない https://t.co/EdhD79gUBA ・1/4でコロナ感染と同等の免疫反応 https://t.co/fzLdWnIL4R ・WHOもより多くの人が接種できるよう1/2接種の研究を推奨 https://t.co/gHT6homnJG https://t.co/EbJniJwvwI
なんだ、ワクチン用量半分、WHOが研究奨励してるじゃないですか(日本経済新聞) https://t.co/ModEutNZ4p 2021-08-10 WHO発表 https://t.co/gHT6homnJG 半ワクチン派を名乗っていこうかな…
@pfamilygal They were giving vaccine doses to humans in tests back in March 2020. https://t.co/SfmI9qe4lB
ほんと今更ではあるんだけど、40歳以下とかはワクチンの投与量半分とかにできなかったんかなぁ… モデルナの投与量決定試験(25/100/250μg)。 25μgの方が発熱とか少ない。投与量100μgに決定。 https://t.co/EdhD79gUBA その半年後の血液検査。25μgでもそこそこ機能。 https://t.co/fzLdWnIL4R https://t.co/BEXyJ4LDQr
@Alba_Grifoni @Dani6020 @SetteLab @profshanecrotty @JMatues Interesting to compare with the Moderna phase-1, dose-escalation (open-label trial), published in November 2020: https://t.co/K9u3AyvVtE https://t.co/UKt0DOYG9C
@InfiniteZox @Sariracha626 @lmlysofia @homesicknoah @NICKIMINAJ Look it up, don't you people love to "do your own research" https://t.co/5iGJBfzZ77
@simon_bazelon I can’t believe this is still up when every quote tweet is about how wrong you are.
RT @ENirenberg: This is really incorrect. For starters determining the optimal dose was done for the vaccine candidates in Phase 1/2 e.g.:…
RT @ENirenberg: This is really incorrect. For starters determining the optimal dose was done for the vaccine candidates in Phase 1/2 e.g.:…
An informative thread about the optimal vaccine dosing regimen debate.
RT @ENirenberg: This is really incorrect. For starters determining the optimal dose was done for the vaccine candidates in Phase 1/2 e.g.:…
RT @ENirenberg: This is really incorrect. For starters determining the optimal dose was done for the vaccine candidates in Phase 1/2 e.g.:…
RT @ENirenberg: This is really incorrect. For starters determining the optimal dose was done for the vaccine candidates in Phase 1/2 e.g.:…
RT @ENirenberg: This is really incorrect. For starters determining the optimal dose was done for the vaccine candidates in Phase 1/2 e.g.:…
RT @DominiekC: Een mooi draadje van iemand die een compleet fout draadje weerlegt, maar de compleet foute tweet heeft ondertussen wel >900…
RT @ENirenberg: This is really incorrect. For starters determining the optimal dose was done for the vaccine candidates in Phase 1/2 e.g.:…
RT @ENirenberg: This is really incorrect. For starters determining the optimal dose was done for the vaccine candidates in Phase 1/2 e.g.:…
RT @ENirenberg: This is really incorrect. For starters determining the optimal dose was done for the vaccine candidates in Phase 1/2 e.g.:…
Een mooi draadje van iemand die een compleet fout draadje weerlegt, maar de compleet foute tweet heeft ondertussen wel >900 likes … “The amount of energy needed to refute bullshit is an order of magnitude bigger than to produce it” (Alberto Brandolini)
RT @ENirenberg: This is really incorrect. For starters determining the optimal dose was done for the vaccine candidates in Phase 1/2 e.g.:…
RT @ENirenberg: This is really incorrect. For starters determining the optimal dose was done for the vaccine candidates in Phase 1/2 e.g.:…
This is really incorrect. For starters determining the optimal dose was done for the vaccine candidates in Phase 1/2 e.g.: https://t.co/EpQ3rsDN12 https://t.co/0dwierOa77 https://t.co/nIxzKJyKdz https://t.co/rRRCo9pJNW
RT @VaccineWatch: 論文はこちらから。 https://t.co/YgOfhimQuO
@NoyesJHumphrey @AndBeyond_N @gerdosi … observing reduced lymphocytes, I think this is just because they didn’t test for them at the right time Source: https://t.co/tzY5J6Qzbr See Page 12/13 of the supplement for lab AEs
@GryphonSavvy @cdc Here you go. https://t.co/pxhoNlcJB5 Will look for final report.
@EricAljets @MonkText @mojalefa_sebati @RWMaloneMD Hahaha have you even looked? I know you won’t click on any of these, so I’ll stop at 5. https://t.co/xdThYZo0kX https://t.co/IxuGHLLUNe https://t.co/qD2nhcqWyQ https://t.co/pdy1TKgl8u https://t.co/FfB
@dokterimun_id Mohon koreksi ya dok, dua2 vaksin mRNA mengodekan full spike protein bukan hanya RBD. Bhkn me'modifikasi'nya bila dibanding wt- AZ punya. mRNA1273 moderna: https://t.co/IpelQmF274 Bntb2-Pfizer https://t.co/cF8v6ZvOz9
@andrew_croxford @ShaunLintern @mark_toshner @samueljlovett yes, it's that way round - more AE 2nd dose with mRNA. Something I always found biologically curious. Implies (to me) that mechanism to AE differs quite a bit between vaccine platforms. https://t.
👇
@2017ceasar @TinFoilAwards @SwordtheChemist @rachy0101 @thereds8 Yes there is, that's why full approval is happening right now. These are questions that are typically studied in phase I. That happened a long time ago. https://t.co/Tn9F24TPnS
@y_tambe 25-100-250で振ったとき、25は、熱でなくなるけど、抗体生産少なそう。ただし、被験者が群あたり15人ずつしかいない。 https://t.co/X4IHbmzOSt
@Xochilt60781450 Here is the Phase 1 safety report from Nov 2020 https://t.co/kmARxlOIpa
@DanSanchez @salva_iborra @JoseMJG @CValdizan @JJAnticomunista @Dr_Pilgrim Admites que pasaron la fase de aminales y todas las correspondientes? https://t.co/nUXAmaSkhv
@DanSanchez @JoseMJG @CValdizan @JJAnticomunista @Dr_Pilgrim "Dice que todas las demas si pasaron" con esto ya veo que te retractas de tu afirmación de que "NO LO HAN PASADO", segundo las de MRNA si que la han pasado: https://t.co/LT2TbIx0Fc Fase 1: https:
@hallangerhans @katieappleseed7 Back in 2020. "An mRNA Vaccine against SARS-CoV-2 — Preliminary Report | NEJM" https://t.co/4Mo01bwnf8
@Castdeath97 @mraustin @Dereklowe Moderna's papers touch on this issue, esp. [3]. No sign of ADE with the original virus strain. [1]: https://t.co/yqMNpBwYP8 [2]: https://t.co/oPdHrhXEs7 [3]: https://t.co/766MNaPIze
RT @ajitjohnson_n: Moderna's most advanced mRNA vaccine against SARS-CoV-2 results are out (n=45). They show that the vaccine produced a ro…
@MvcltsD @schalio @dupondbernard2 @vellaviens @AdresanSophie @wargonm Donc test des vaccins depuis Juillet 2020 : https://t.co/jty5aoZsQ3 Historiquement, cas d'effets secondaires post vaccinal (lire description et commentaires pour les sources) : https://
@karriT4kids @HoodieKells @STLBluesChirp @StLouisBlues Google is your friend. But: Summary of recent advances: https://t.co/hPBxmaXtYC Another on lessons learned, specifically references the Tseng/2012 study among a multitude of others: https://t.co/f7EQ
RT @bencowling88: Here are data from Moderna’s mRNA-1273 vaccine. Figure 2 from the paper indicates that immune responses after two doses o…
@commonsense5050 @pratyushbuddiga Friend, it has. “The 45 enrolled participants received their first vaccination between March 16 and April 14, 2020“ https://t.co/33vFjUqMap #TheMoreYouKnow
@timmo74 @Bobette67259511 @sigfridvshrink @wappiehoekje @Marco111267 · 2020: mRNA-1273 in fase I/II (45 vrijwilligers) https://t.co/pW1cEU4tUA · 2020: BNT162b in fase III (44.000 vrijwilligers) https://t.co/CoXgN1Y8E5 · 2020: mRNA-1273
@MorganRadford @DollyParton American treasure🙏 https://t.co/yCo44DIKNL https://t.co/Uvsa9dAXLO
@Naboleon_3 @viag42 @Poulin2012 C est bien ce que je disais -----> https://t.co/5pT6r9d2Mg
@hankhepler @RichardGrenell That’s the Pfizer data. The Moderna data looks similar: https://t.co/lZZte1Pzug https://t.co/i37517pYVc
https://t.co/D3lEJe3MM3 "After the second vaccination, no participants in the 25-μg group, 6 (40%) in the 100-μg group, and 8 (57%) in the 250-μg group reported fever; one of the events (maximum temperature, 39.6°C) in the 250-μg group was graded severe."
RT @FactsDoMatter4: For those saying “we only have a few months of covid vaccine data”: The first clinical trials of the covid vaccine wer…
For those saying “we only have a few months of covid vaccine data”: The first clinical trials of the covid vaccine were published in July 2020. https://t.co/bwzuf7cBoF
RT @bioeditores: Hemos sido testigos del acortamiento de 6 años de trabajo en 6 meses. ¿Podría esta mismo esfuerzo colaborativo humano-cien…
@MesGourmandsD_ @lestrepublicain Les recherches ont commencé dès les premiers jours de 2020, puisque la maladie s’est déclarée dès fin 2019 https://t.co/SKGYKbJ5xB
RT @JuanitoEpidemio: Voy a hacer un hilo para las personas que no son del sector salud, con el fin de explicar de forma muy sencilla, qué e…
RT @JuanitoEpidemio: Voy a hacer un hilo para las personas que no son del sector salud, con el fin de explicar de forma muy sencilla, qué e…
@Jane_All_Trades @RWMaloneMD It’s interesting because the referenced paper does not suggest that. https://t.co/sX3mC1Q0mo https://t.co/GgV6UmcK0L
RT @takeshi_kine: #第一三共 #石井健 #mRNAワクチン 情報開示が全く無い💢 1相治験→投与量、中和抗体力価(回復期患者血清との比較)、主要な副反応 スパイクタンパク質の発現コンストラクト内に #Maclellan 教授らのS-2P改変を採用?→Pfize…
#第一三共 #石井健 #mRNAワクチン 情報開示が全く無い💢 1相治験→投与量、中和抗体力価(回復期患者血清との比較)、主要な副反応 スパイクタンパク質の発現コンストラクト内に #Maclellan 教授らのS-2P改変を採用?→Pfizer、Moderna、Novavax、J&Jは採用。 モデルナ1相 https://t.co/mFHVn11NwL
RT @bencowling88: Here are data from Moderna’s mRNA-1273 vaccine. Figure 2 from the paper indicates that immune responses after two doses o…
An mRNA Vaccine against SARS-CoV-2 - Preliminary Report - PubMed https://t.co/xTk6JdqVix
モデルナワクチンNEJEMの論文を改めて読んで今日の二回目接種に備えます。 https://t.co/eR9qELukkT
RT @bencowling88: Here are data from Moderna’s mRNA-1273 vaccine. Figure 2 from the paper indicates that immune responses after two doses o…
For #Moderna vaccine, a dose of 25 μg conferred GMT PRNT80 titers (inverse of d concentration of serum needed to reduce no. of plaques by 80%) of 340 at 14 days after 2nd dose, compared with a value of 654 for the group that received standard dose 6/
RT @bencowling88: Here are data from Moderna’s mRNA-1273 vaccine. Figure 2 from the paper indicates that immune responses after two doses o…
Here are data from Moderna’s mRNA-1273 vaccine. Figure 2 from the paper indicates that immune responses after two doses of 25µg (1/4 dose) are slightly lower than after two doses of 100µg (full dose). No data in this study on 50µg (i.e. half dose) (11/20)
This is an under-appreciated travesty. FDA bears most of the blame here. Moderna's phase II trial (published Jul 14 2020 on https://t.co/AtZcNvBY59 : https://t.co/uq3yCWvtHv) indicated that half Moderna doses are almost as effective as full! See also:
NEJMでは、SARS-CoV-2に対するmRNAワクチン について、有害事象は軽度、中等度に分類されるものはあれど、重篤な有害事象は認められなかった。としている。 ワクチン摂取との天秤にかけることは必要。 摂取せずに死ぬのがワーストかな。 https://t.co/3nsxiZ0LFn
@RWMaloneMD Dear Robert, I am aware the data can be improved but it seems they also studied it. 👇 Interestingly, none of them talk about pharmacokinetics... 🤷 https://t.co/pdAllyPA4c
@rzioni @n83SVTCAxNiWn54 @AliceDrori @naftalibennett https://t.co/D4OwaZUrCR המאמר משלב I של מודרנה, פיסקה על זה שכן מצאו תגובה תאית. בחיסון נגד שפעת כתבו אפילו באבסטרקט שלא מצאו תגובה תאית וכאן כן מצאו. זה שונה וראו את זה מההתחלה. יש עוד ניסויים שהראו גם
@BelennaGrecia @victorramonmat Obviamente este señor no se ha molestado en buscar mucho. A mí no me asombra, habría que revisar sus conflictos de interés en este asunto. https://t.co/T4tpYMypzv https://t.co/AIWt7pFknO
Science, you bird brains believe anything you read. I whole heartily bow down to your knowledge of vaccines. Wow, a whole year of checking out the stuff. Go ahead & jab buddy. Nice job of Goggling and cut & paste. That makes it real. BTW: Not appro
His mentions are mostly antivax clown fiesta, but occasionally have useful data. For example an earlier post claimed no dosage grading was done, which turned out to be incorrect. https://t.co/wOTeENJyCr
RT @IAmSamFin: @RWMaloneMD Is this not the study you’re looking for by moderna? https://t.co/s9jq7fuHig https://t.co/QiqOlNJu7t
@RWMaloneMD Fixing Twitter threading https://t.co/VT5HVzIRiH
@RWMaloneMD Is this not the study you’re looking for by moderna? https://t.co/s9jq7fuHig https://t.co/QiqOlNJu7t
#mRNAワクチン #モデルナ #大規模集団接種 接種後24時間経過、今がピークかな?(24時間)腋窩リンパ節の腫脹は今のところ無い。 今正にこの論文の報告通りの事象が身体の中で始まっている❣️ https://t.co/mFHVn11NwL
@kabayan_ako @TrevoDFuoco @raissawriter https://t.co/wrAdyqDCMh source about mechanism of action ng mRNA vaccine. Basahin mo ha o need mo iinterpret ko at isimplify ko para sa imbecile mong utak?
RT @takeshi_kine: @TomoTanakaLTx #mRNAvaccine #PfizerBionTech #Moderna #Katalinkariko #NianshuangWang モデルナの1相治験の報告を読んだ。一回目接種後2週間以内にRBD/S-2…
RT @BVeralu: Vacina cov$d é inútil após 3 meses: Anticorpos desaparecem, vírus sofre mutação - com efeitos colaterais . Os resultados da pe…
RT @BVeralu: Vacina cov$d é inútil após 3 meses: Anticorpos desaparecem, vírus sofre mutação - com efeitos colaterais . Os resultados da pe…
RT @BVeralu: Vacina cov$d é inútil após 3 meses: Anticorpos desaparecem, vírus sofre mutação - com efeitos colaterais . Os resultados da pe…
RT @BVeralu: Vacina cov$d é inútil após 3 meses: Anticorpos desaparecem, vírus sofre mutação - com efeitos colaterais . Os resultados da pe…
RT @BVeralu: Vacina cov$d é inútil após 3 meses: Anticorpos desaparecem, vírus sofre mutação - com efeitos colaterais . Os resultados da pe…
RT @BVeralu: Vacina cov$d é inútil após 3 meses: Anticorpos desaparecem, vírus sofre mutação - com efeitos colaterais . Os resultados da pe…
If the mRNA vaccine was made from the SARS genome it should protect against all variants? "Vaccine development was initiated after the SARS-CoV-2 genome was posted on January 10, 2020;" https://t.co/5w7Iez8gWT
pfizer-BNT phase 1 45 adults, 18-55 https://t.co/PpYHA9lURK
Tuve una discusión con #antivacunas y busqué de lo general a lo específico info con fuentes serias para debatir. Les comparto: https://t.co/61Gx5Hjlin https://t.co/WgSATFZAHf https://t.co/FmRGdZ9jnu https://t.co/bJPNRUl7Se Todo para q + gente se va