@TRobinsonNewEra Sex hormones are metabolized via the same biochemical pathways as antidepressants, which many of these kids are on. This can cause interactions preventing normal metabolism, levels rise, and the outcomes can be devastating. https://t.co/Nj
@libsoftiktok @GuntherEagleman Sex hormones and anti-depressant share many metabolic pathways. Interactions can impair metabolism, as can mutations in genes called CYP450. The results can be disastrous, as documented in an article I co-wrote. https://t.co/
@libsoftiktok The trans hormones and multiple anti-depressants are metabolized by the same CYP450 enzymes that can have any number of mutations. Both interactions and mutations can prevent normal metabolism, driving levels into overdose territory with ens
@ChayaRaichik10 @SebGorka In case anyone’s interested, here’s an article that provides a mechanism for how impaired metabolism of antidepressants can drive people around the bend. https://t.co/Nja6ZB0IYo