Seroprevalence of Abs to SARSCoV2 in 10 Sites in the US:detectable SARSCoV2 Abs ranged from 1.0% in SF Bay area,to 6.9% in NYC. 6-24 times⬆️infections were estimated/site with seroprevalence than with (COVID-19) case report data. https://t.co/xGTcbipor5
RT @SixandLaura: Important 🧵 on research methods of #CDC #seroprevalence studies Concerns described also apply to the #EVALI #BAL studies:…
@erthwjim @blowyburrito @MattLombardoNFL So, you 🤡s want to stick with just what the CDC says, because they are the ones who handle the data for the “country where the NFL plays”, https://t.co/ZyeUnTzVce
RT @DiseaseEcology: Could possibly test hypothesis H1 w/ reliable serological study. Need: -Ab assay that doesn't show fast sero-reversion,…
@danjcyr @RexArcherMD You might want reexamine your <1% assumption... Just saying... https://t.co/1SLONGBnMa
Important 🧵 on research methods of #CDC #seroprevalence studies Concerns described also apply to the #EVALI #BAL studies: Convenience sample (non-random) Condition of material (leftover frozen) Biases unaddressed Small N = uninterpretable data 7/21/20
RT @DiseaseEcology: Could possibly test hypothesis H1 w/ reliable serological study. Need: -Ab assay that doesn't show fast sero-reversion,…
Could possibly test hypothesis H1 w/ reliable serological study. Need: -Ab assay that doesn't show fast sero-reversion, like many nucleocapsid tests seem to @isabelrodbar -unbiased serosurvey https://t.co/RmXgpgTL8U
@GordBolton @lraitt @99freemind Also the Sunde article is in error. The article cited https://t.co/iVenKmBvv3 does not show the virus was already "widespread" in the US in December 2019. The Italian study is interesting but I would like to see sequence d
@Flying__Doc Sowohl die amerikanische CDC als auch die WHO gehen von einer Dunkelziffer #SarsCov2 Infektionen x10 aus. D.h. bei einer weltweiten CFR von ~2% wären wir bei einer IFR wie von der WHO veröffentlicht von ~0.2% -> Schwere Grippe! https://t.c
4/S Commendably, the paper's authors know this. So they choose "community" studies that tried to get a representative sample by selecting people are random. But they also use a CDC study with non-representative samples. https://t.co/Zqkz5c9jiT https://
RT @AtomsksSanakan: @DiseaseEcology @GidMK @BillHanage @CovidSerology This paper will likely be doing the rounds. They're some improveme…
@DiseaseEcology @GidMK @BillHanage @CovidSerology This paper will likely be doing the rounds. They're some improvements over the initial JAMA paper, but the authors miss that the New York study uses a convenience sample. https://t.co/Zqkz5c9jiT https:
US seroprevalence study,proportion of seroreactive to SARSCoV2 spike protein Abs ranged from 1% SF,7% NYC.The estimated no of infection ranged:6-24 time the no of reported cases;7 sites,estimated >10 times more infection occurred than the no reported ca
RT @JAMAInternalMed: In this US seroprevalence study conducted mid-March-to-May 2020, the estimated number of #SARSCoV2 infections ranged f…
This study is also in line to the recently published article from a team in #Kenya. The seroprevalence is way higher than expected. 6-24x more ppl are seropositive. Also the authors report that cross reactivity with other coronaviruses is below the limit o
RT @JAMAInternalMed: In this US seroprevalence study conducted mid-March-to-May 2020, the estimated number of #SARSCoV2 infections ranged f…
RT @JAMAInternalMed: In this US seroprevalence study conducted mid-March-to-May 2020, the estimated number of #SARSCoV2 infections ranged f…
In this US seroprevalence study conducted mid-March-to-May 2020, the estimated number of #SARSCoV2 infections ranged from 6 to 24 times the number of reported cases in 12 US metropolitan areas @CDCgov https://t.co/ASWmixwyDr
@peteryared @semil Link goes to a Bloomberg article that doesn't list est. prevalence for any of those three states. It does link to CDC and JAMA publication showing about a 1% rate in SF and a 2.2% rate in South Florida. https://t.co/PmmjMuIhF5
4. In the US, serological survey at 10 sties found that estimated infections ranges from 6.0X to 23.8X of reported cases. https://t.co/ojwKSBgVmd
@nowmikereiter @KEVINTICE7 @MikePerryavatar The CDC estimated that they are undercounting Covid infections from anywhere between 6 to 24 times the amount. Or do you only choose which CDC statistics fit your "science"? https://t.co/Ge9vWu0a2v
@Ben_raddatz Estimating true prevalence of covid 19 in the community, as only a fraction actually get tested. This study estimated actual number of infections ranged from 6-24x (!) the number of reported cases: https://t.co/3NPgAYVR9M I used 5 as a conser
@ColoidesOxigeno @TenOldMen @realDonaldTrump COVID19 Undercounting studies: 1.https://t.co/kBMsgJwp7l 2.https://t.co/UaeputQ0LF
@migueldeicaza fixed my numbers - thanks: https://t.co/J8lfpqaGUb
Testing under-counts SARS CoV2 by 10x (https://t.co/0sjQ29MASV), herd immunity's at 94% (https://t.co/wBH2ZU6Qgp), we have 16M positive tests rising by 28K/day. If we flatten the curve we'll be immune by Feb 6th, if rates keep rising much sooner. Why both
Whatever your COVID test rate is multiple by 10 for actual number of infections. Many mildy/asymptomatic but infectious @cupalcare Seroprevalence of Antibodies to SARS-CoV-2 in 10 Sites in the United States, 2020 https://t.co/zL6EnO4M2T via @JAMAInternalM
@youyanggu But: https://t.co/QfKvsyISMh via @JAMAInternalMed https://t.co/rh8jYjAfK5 via @IDSAInfo (re: already exposed/recovered) And: https://t.co/mcGWghSOle via @ScienceMagazine https://t.co/6HnQ3Q77bd via @NatRevImmunol (re: pre-existing immunity)
@DBelardoMD @deepfakefdr @RyanLum @GidMK So I dug up the study that @DrDavidKatz was likely talking about and there are very serious caveats. This was not based on a random sample of people but people who thought they might have been sick with COVID! That
Diff method. Diff time. Similar answer (via @CDCgov) From seroprevalence Mar-May: actual #COVID19 cases ~10x higher! https://t.co/QfKvsyISMh via @JAMAInternalMed From probabilistic multiplier in Sep: actual #COVID cases ~8x higher! https://t.co/rh8jYjAf
RT @hereforthemad: @IAmTheActualET Missouri had the highest antibodies out of any state in April. 24 positive antibody test to one positive…
RT @hereforthemad: @IAmTheActualET Missouri had the highest antibodies out of any state in April. 24 positive antibody test to one positive…
@JeanneLenzer1 @beyerstein @ShannonBrownlee @sdbaral @BMJ_EBM Re: “yet none of them were attacked the way Ioannidis was” 1) The NY grocery store study wasn’t anyway near as badly designed as the Santa Clara study. 2) Residual sera studies were criticized
@KrutikaKuppalli I remember this from July and have repeatedly heard it mentioned with the admonition that it’s likely not this much higher but evidence of a significant larger population of infections. https://t.co/jP9vQ4E2vk?
RT @DiseaseEcology: @andrewazman @jLewnard @JAMAInternalMed Perhaps even more important than lumping 0-17 is pop sampled - these are residu…
What a seriously seriously good thread!
@andrewazman @jLewnard @JAMAInternalMed Perhaps even more important than lumping 0-17 is pop sampled - these are residual sera from screening. Hugely biased pop that I think make results nearly uninterpretable (thread on 1st paper from this project: https:
@CuriousDukes The CDC estimated 10 times as many actual cases as test-confirmed cases. Study here: https://t.co/hq4OkmszVv Chicago's experts estimate it's closer to 5-7 times as many cases here since our testing is better than most.
@Chris42122520 @Gialde @reneelsamson @10dollarbeer @ddnarich @LavenderProf If you insist... Actual cases is anywhere from 6 to 24 times the # of confirmed cases. Using those numbers the worst case average death rate is 0.36%. Most of the deaths appear in
RT @DFisman: Also: this is from the spring wave and looks like we did capture around 1 in 5 infections in Ontario...pretty good, around the…
RT @DFisman: Also: this is from the spring wave and looks like we did capture around 1 in 5 infections in Ontario...pretty good, around the…
RT @DFisman: Also: this is from the spring wave and looks like we did capture around 1 in 5 infections in Ontario...pretty good, around the…
RT @DFisman: Also: this is from the spring wave and looks like we did capture around 1 in 5 infections in Ontario...pretty good, around the…
Also: this is from the spring wave and looks like we did capture around 1 in 5 infections in Ontario...pretty good, around the same as Connecticut. https://t.co/hR2Zhi5u8Z Again, may be an overestimate due to donors being different than the pop as a whol
این یه نمونه پژوهش سرولوژیک با نمونه ۱۶ هزار نفره و تخمین تعداد واقعی مبتلاشدگان بر اساس تعداد افرادی که آنتیبادی دارن. https://t.co/DPRUR80El7
NYtimes reports that 1 in 26 persons have tested for COVID in Cache County Utah. If rates of https://t.co/6yN2JMIPJ9 apply, ten times as many infections are more likely. Mask up, distance, do not social gather outside household, wash hands 20 seconds, and
@sunbingfa @cmyeaton This report shows that there are millions and millions infected. It could be more than 65million
@MikeCulpeper @BillKruck @JayJJ1990 @benshapiro ill post it for a second time. https://t.co/OmonKxCQwv
@MikeCulpeper @BillKruck @JayJJ1990 @benshapiro It could be or couldnt be, it was a study done that warns that estimates could be higher than what the CDC estimates. Maybe he was mistaken on who had said it, but the CDC has been called out on the 40% stat
Related: https://t.co/Qqzk2x5Zky
First, we have known for quite some time that many cases of #Covid19 are not detected. Early serological work by the @CDCgov placed this at 10:1, i.e., 10 actual cases for each documented case. Havers et al, @JAMA_current: https://t.co/JoVeVkRVel
https://t.co/yVvFChwYYw https://t.co/JoUXHZM65K Most US sites had seroprevalence below 10% https://t.co/Ut4WBuG6Qv
@CFKSherry @chrisvanderveen Yes. CDC study was domestic. The numbers are pretty similar https://t.co/wXK0am3lFc
@asafperes @chrisvanderveen Yes, the number of people with antibodies is likely higher now. https://t.co/wXK0am3lFc
@MichaelYeadon3 Here’s one report: https://t.co/SXHEwN1O6u
One way to get a better picture is with seroprevalence studies. https://t.co/SI8Jnu7bKg "Six to 24 times more infections were estimated per site with seroprevalence than with coronavirus disease 2019 (COVID-19) case report data"
RT @DeaceProducer: With 28,399 cases reported in the aforementioned demo, that's a CFR of .02%, with the IFR likely being ~10x lower, accor…
@revlarz This article from the AMA is linked in the article, stating an actual infection rate 10x the recorded positive tests...🤦♂️ Anyone grounded in reality knows what’s going on. https://t.co/Lt1O9rzCKB
RT @DeaceProducer: With 28,399 cases reported in the aforementioned demo, that's a CFR of .02%, with the IFR likely being ~10x lower, accor…
With 28,399 cases reported in the aforementioned demo, that's a CFR of .02%, with the IFR likely being ~10x lower, according to the CDC. Sources: https://t.co/vWizZ0SDWd https://t.co/uXmuI4v0Xj
@billkole @hankschulman Goto the CDC people. Read what they publish for yourselves. https://t.co/h2pCrzfSMk
@BillShaikin If you are in the age group of 18-60 years old you will have a 99.998% of surviving covid. Overall 98% survival rate. Most people are Asymptomatic (no symptoms). It is estimated that 15% of the 🇺🇸 population is already infected. https://t.co/
@dasslappy77 @Amati9 @MeetThePress @chucktodd got it. we have discovered all cases of covid by testing. https://t.co/ezq5mIIw4d
@dwainer1 @Ohskeens @jasonhatch20 @LoJackson94 @ProfDFrancis "For most sites, it is likely that greater than 10 times more SARS-CoV-2 infections occurred than the number of reported COVID-19 cases; most persons in each site, however, likely had no detectab
@sardinest @2014_judi @scrowder "For most sites, it is likely that greater than 10 times more SARS-CoV-2 infections occurred than the number of reported COVID-19 cases; most persons in each site, however, likely had no detectable SARS-CoV-2 antibodies." h
So this was over two months ago. That was 50 million “cases” & now there’s at least 70 million. This is a good thing, as long as we let it spread through the invulnerable to protect the vulnerable. Like Oxford Epidemiologist Sunetra Gupta said https:
@ASlavitt There is actually around 50million who’ve been infected
@Patriot7779311 @MKP83500270 @hereweg80828046 @thehill Herd immunity has worked in Sweden and if everything was open and we spent our resources on protecting the super vulnerable we could be there soon. Following lockdowns don’t work. FL never did CA did a
RT @VincentRK: But the proportion of people who have been exposed is very low even in hotspots. Less than 10%. Does this mean >90% of us ar…
@shananalla @ThinkActTank @Dharmen46587056 @SajidJa23282468 @prat @docraviw @ProfSomashekhar @drasmalhi @giridar100 @TRRaju1 @rajnishgupta59 @ICMRDELHI @ProfBhargava @ScienceTales @RogueRad I have read the paper. It is only a convenience sample by commerci
RT @VincentRK: But the proportion of people who have been exposed is very low even in hotspots. Less than 10%. Does this mean >90% of us ar…
RT @VincentRK: But the proportion of people who have been exposed is very low even in hotspots. Less than 10%. Does this mean >90% of us ar…
Seroprevalence of Antibodies to SARS-CoV-2 in 10 Sites in the United States, March 23-May 12, 2020 https://t.co/E0wNY1tPSc #COVID19seroprevalence
RT @VincentRK: But the proportion of people who have been exposed is very low even in hotspots. Less than 10%. Does this mean >90% of us ar…
RT @VincentRK: But the proportion of people who have been exposed is very low even in hotspots. Less than 10%. Does this mean >90% of us ar…
But the proportion of people who have been exposed is very low even in hotspots. Less than 10%. Does this mean >90% of us are still susceptible? And if so, why are cases decreasing? https://t.co/nUQVnlPJ4Z 3/ https://t.co/ybwHdLhj77
RT @TedGenoways: There have been 6.5 million confirmed cases of #COVID19 in the US. A study of coronavirus antibodies in blood samples coll…
There have been 6.5 million confirmed cases of #COVID19 in the US. A study of coronavirus antibodies in blood samples collected found that the real number ranged from 6 to 24 times the number of reported cases, with most sites at more than 10 times higher.
@veebee1010 @DontBeACutiePi @StephenBDugmore Sure, that makes sense, but the best way to reduce bias is to enlarge the sample, no? Less effect of any bias due to a reduced extrapolation. While not a “study,” these results account for 1.5M people. Still, h
هناك مصدر يتابع هذه الدراسات بشكل دوري https://t.co/x02qTDVIrL https://t.co/wbr3kV7Txu المصادر https://t.co/5LvfgE1Jiv https://t.co/ENQNbI7LAt https://t.co/vwvpFY1O58 https://t.co/OVuLrVNODY
@BillHanage @NewYorker might be this JAMA article? Was in the news a while back https://t.co/gN4NoGGq7S
@complexsimon @CassanoraL @Joyhenderson78 @bgailitis @Sflecce No 2nd “wave” is term people are using for when case numbers go up again due to relaxing of physical distancing measures this fall (assuming we continue virus testing at or above current). JAMA
@CassanoraL @Joyhenderson78 @bgailitis @Sflecce Nobody in TPH or TDSB valued our children or teachers or their families enough to request of the Federal Government access for these purchased 140,000 antibody tests to determine the community actual spread.
@GioeleS @ASlavitt https://t.co/EKvgpMG3GT Do some research. There is more to just listening to some who only have your same beliefs. Don’t be married to your ideas and be open minded. More and more people are realizing the truth
RT @VincentRK: A large seroprevalence study found that we may be underestimating number of COVID cases in the US by 10-fold. What does this…
RT @VincentRK: A large seroprevalence study found that we may be underestimating number of COVID cases in the US by 10-fold. What does this…
RT @VincentRK: A large seroprevalence study found that we may be underestimating number of COVID cases in the US by 10-fold. What does this…
@VeniceMase https://t.co/EKvgpMG3GT Pay attention! What’s the actual risk?
RT @VincentRK: A large seroprevalence study found that we may be underestimating number of COVID cases in the US by 10-fold. What does this…