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The cat lipocalin Fel d 7 and its cross-reactivity with the dog lipocalin Can f 1

Overview of attention for article published in Allergy, July 2016
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#47 of 3,092)
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (96th percentile)

Mentioned by

news
8 news outlets
twitter
1 tweeter
facebook
1 Facebook page

Citations

dimensions_citation
26 Dimensions

Readers on

mendeley
18 Mendeley
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Title
The cat lipocalin Fel d 7 and its cross-reactivity with the dog lipocalin Can f 1
Published in
Allergy, July 2016
DOI 10.1111/all.12955
Pubmed ID
Authors

D. Apostolovic, S. Sánchez-Vidaurre, K. Waden, M. Curin, J. Grundström, G. Gafvelin, T. Cirkovic Velickovic, H. Grönlund, W. R. Thomas, R. Valenta, C. Hamsten, M. van Hage

Abstract

We investigated the prevalence of sensitization to the cat lipocalin Fel d 7 among 140 cat-sensitized Swedish patients and elucidated its allergenicity and cross-reactivity with the dog lipocalin Can f 1. Sixty-five of 140 patients had IgE to rFel d 7 whereof 60 also had IgE to rCan f 1. A moderate correlation between IgE levels to rFel d 7 and rCan f 1 was found. rFel d 7 activated basophils in vitro and inhibited IgE-binding to rCan f 1 in 4/13 patients, whereas rCan f 1 inhibited IgE-binding to rFel d 7 in 7/13 patients. Fel d 7 and Can f 1 showed high similarities in protein structure and epitopes in common were found by using cross-reactive antisera. Fel d 7 is a common allergen in a Swedish cat-sensitized population that cross-reacts with Can f 1, and may contribute to symptoms in cat- but also in dog-allergic patients. This article is protected by copyright. All rights reserved.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 18 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 50%
Professor 1 6%
Student > Doctoral Student 1 6%
Other 1 6%
Student > Ph. D. Student 1 6%
Other 2 11%
Unknown 3 17%
Readers by discipline Count As %
Immunology and Microbiology 5 28%
Biochemistry, Genetics and Molecular Biology 3 17%
Agricultural and Biological Sciences 2 11%
Veterinary Science and Veterinary Medicine 1 6%
Unspecified 1 6%
Other 2 11%
Unknown 4 22%

Attention Score in Context

This research output has an Altmetric Attention Score of 62. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 October 2016.
All research outputs
#231,055
of 12,342,443 outputs
Outputs from Allergy
#47
of 3,092 outputs
Outputs of similar age
#9,729
of 275,101 outputs
Outputs of similar age from Allergy
#3
of 85 outputs
Altmetric has tracked 12,342,443 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,092 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.3. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 275,101 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 85 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.