Title |
Field comparison of OraQuick® ADVANCE Rapid HIV-1/2 antibody test and two blood-based rapid HIV antibody tests in Zambia
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Published in |
BMC Infectious Diseases, August 2012
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DOI | 10.1186/1471-2334-12-183 |
Pubmed ID | |
Authors |
Dalila Zachary, Lawrence Mwenge, Monde Muyoyeta, Kwame Shanaube, Albertus Schaap, Virginia Bond, Barry Kosloff, Petra de Haas, Helen Ayles |
Abstract |
Zambia's national HIV testing algorithm specifies use of two rapid blood based antibody assays, DetermineHIV-1/2 (Inverness Medical) and if positive then Uni-Gold Recombigen HIV-1/2 (Trinity Biotech). Little is known about the performance of oral fluid based HIV testing in Zambia. The aims of this study are two-fold: 1) to compare the diagnostic accuracy (sensitivity and specificity) under field conditions of the OraQuick ADVANCE Rapid HIV-1/2 (OraSure Technologies, Inc.) to two blood-based rapid antibody tests currently in use in the Zambia National Algorithm, and 2) to perform a cost analysis of large-scale field testing employing the OraQuick. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Japan | 4 | 57% |
United States | 1 | 14% |
Unknown | 2 | 29% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 7 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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India | 1 | <1% |
Unknown | 101 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 20 | 20% |
Student > Master | 15 | 15% |
Student > Ph. D. Student | 13 | 13% |
Student > Postgraduate | 10 | 10% |
Other | 7 | 7% |
Other | 22 | 22% |
Unknown | 15 | 15% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 32 | 31% |
Social Sciences | 15 | 15% |
Agricultural and Biological Sciences | 9 | 9% |
Nursing and Health Professions | 8 | 8% |
Immunology and Microbiology | 3 | 3% |
Other | 15 | 15% |
Unknown | 20 | 20% |