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Extracellular adenosine signaling induces CX3CL1 expression in the brain to promote experimental autoimmune encephalomyelitis

Overview of attention for article published in Journal of Neuroinflammation, August 2012
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Title
Extracellular adenosine signaling induces CX3CL1 expression in the brain to promote experimental autoimmune encephalomyelitis
Published in
Journal of Neuroinflammation, August 2012
DOI 10.1186/1742-2094-9-193
Pubmed ID
Authors

Jeffrey H Mills, Leah M Alabanza, Deeqa A Mahamed, Margaret S Bynoe

Abstract

Multiple sclerosis and its animal model experimental autoimmune encephalomyelitis (EAE) are debilitating neuroinflammatory diseases mediated by lymphocyte entry into the central nervous system (CNS). While it is not known what triggers lymphocyte entry into the CNS during neuroinflammation, blockade of lymphocyte migration has been shown to be effective in controlling neuroinflammatory diseases. Since we have previously shown that extracellular adenosine is a key mediator of lymphocyte migration into the CNS during EAE progression, we wanted to determine which factors are regulated by adenosine to modulate EAE development.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
South Africa 1 2%
Unknown 54 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 16 29%
Student > Ph. D. Student 10 18%
Student > Master 5 9%
Professor > Associate Professor 4 7%
Other 4 7%
Other 6 11%
Unknown 10 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 16 29%
Biochemistry, Genetics and Molecular Biology 9 16%
Neuroscience 7 13%
Medicine and Dentistry 4 7%
Chemistry 2 4%
Other 5 9%
Unknown 12 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 August 2012.
All research outputs
#18,312,024
of 22,673,450 outputs
Outputs from Journal of Neuroinflammation
#2,047
of 2,605 outputs
Outputs of similar age
#128,523
of 167,363 outputs
Outputs of similar age from Journal of Neuroinflammation
#43
of 57 outputs
Altmetric has tracked 22,673,450 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,605 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 12th percentile – i.e., 12% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 167,363 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 57 others from the same source and published within six weeks on either side of this one. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.