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Efficacy of lactulose in the prophylaxis of hepatic encephalopathy in cirrhotic patients presenting gastrointestinal bleeding

Overview of attention for article published in Revista da Associação Médica Brasileira, June 2016
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1 tweeter

Citations

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35 Mendeley
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Title
Efficacy of lactulose in the prophylaxis of hepatic encephalopathy in cirrhotic patients presenting gastrointestinal bleeding
Published in
Revista da Associação Médica Brasileira, June 2016
DOI 10.1590/1806-9282.62.03.243
Pubmed ID
Authors

Felipe Toyama Aires, Paola Teruya Ramos, Wanderley Marques Bernardo

Abstract

Hepatic encephalopathy (HE) is a bad prognostic factor in patients with liver cirrhosis and its incidence is associated with several triggering factors being the most prevalent gastrointestinal bleeding. Lactulose, despite its questionable efficacy in the literature, is considered a first line treatment in patients with HE. To evaluate the effectiveness of lactulose in preventing HE in cirrhotic patients with gastrointestinal bleeding. A systematic review of the literature using the Medline scientific database. Only randomized controlled clinical trials evaluating the efficacy of lactulose for HE prophylaxis in cirrhotic patients with gastrointestinal bleeding were included. The incidence of HE in the intervention group was 7%, while the control group was 26% (p=0.01). There was no significant difference in the incidence of mortality in the group treated with lactulose compared to the group that was not treated (p=0.48). Administering lactulose to cirrhotic patients with upper gastrointestinal bleeding reduces the incidence of hepatic encephalopathy.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 35 100%

Demographic breakdown

Readers by professional status Count As %
Other 7 20%
Student > Bachelor 6 17%
Student > Master 5 14%
Researcher 3 9%
Student > Doctoral Student 3 9%
Other 6 17%
Unknown 5 14%
Readers by discipline Count As %
Medicine and Dentistry 16 46%
Pharmacology, Toxicology and Pharmaceutical Science 6 17%
Nursing and Health Professions 2 6%
Computer Science 1 3%
Biochemistry, Genetics and Molecular Biology 1 3%
Other 2 6%
Unknown 7 20%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 June 2016.
All research outputs
#11,192,331
of 12,577,171 outputs
Outputs from Revista da Associação Médica Brasileira
#327
of 452 outputs
Outputs of similar age
#218,395
of 262,622 outputs
Outputs of similar age from Revista da Associação Médica Brasileira
#8
of 10 outputs
Altmetric has tracked 12,577,171 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 452 research outputs from this source. They receive a mean Attention Score of 2.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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