Title |
Goat milk with and without increased concentrations of lysozyme improves repair of intestinal cell damage induced by enteroaggregative Escherichia coli
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Published in |
BMC Gastroenterology, August 2012
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DOI | 10.1186/1471-230x-12-106 |
Pubmed ID | |
Authors |
Eunice B Carvalho, Elizabeth A Maga, Josiane S Quetz, Ila FN Lima, Hemerson YF Magalhães, Felipe AR Rodrigues, Antônio VA Silva, Mara MG Prata, Paloma A Cavalcante, Alexandre Havt, Marcelo Bertolini, Luciana R Bertolini, Aldo AM Lima |
Abstract |
Enteroaggregative Escherichia coli (EAEC) causes diarrhea, malnutrition and poor growth in children. Human breast milk decreases disease-causing bacteria by supplying nutrients and antimicrobial factors such as lysozyme. Goat milk with and without human lysozyme (HLZ) may improve the repair of intestinal barrier function damage induced by EAEC. This work investigates the effect of the milks on intestinal barrier function repair, bacterial adherence in Caco-2 and HEp-2 cells, intestinal cell proliferation, migration, viability and apoptosis in IEC-6 cells in the absence or presence of EAEC. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 2% |
United States | 1 | 2% |
Unknown | 40 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 5 | 12% |
Student > Master | 5 | 12% |
Researcher | 4 | 10% |
Student > Bachelor | 3 | 7% |
Student > Postgraduate | 3 | 7% |
Other | 11 | 26% |
Unknown | 11 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 11 | 26% |
Biochemistry, Genetics and Molecular Biology | 6 | 14% |
Immunology and Microbiology | 3 | 7% |
Veterinary Science and Veterinary Medicine | 2 | 5% |
Medicine and Dentistry | 2 | 5% |
Other | 4 | 10% |
Unknown | 14 | 33% |