Title |
Pathogenesis of Cardiovascular and Metabolic Diseases: Are Fructose-Containing Sugars More Involved Than Other Dietary Calories?
|
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Published in |
Current Hypertension Reports, April 2016
|
DOI | 10.1007/s11906-016-0652-7 |
Pubmed ID | |
Authors |
Robin Rosset, Anna Surowska, Luc Tappy |
Abstract |
There is increasing concern that sugar consumption may be linked to the development of metabolic and cardiovascular diseases. There is indeed strong evidence that consumption of energy-dense sugary beverages and foods is associated with increased energy intake and body weight gain over time. It is further proposed that the fructose component of sugars may exert specific deleterious effects due to its propension to stimulate hepatic glucose production and de novo lipogenesis. Excess fructose and energy intake may be associated with visceral obesity, intrahepatic fat accumulation, and high fasting and postprandial blood triglyceride concentrations. Additional effects of fructose on blood uric acid and sympathetic nervous system activity have also been reported, but their link with metabolic and cardiovascular diseases remains hypothetical. There is growing evidence that fructose at physiologically consumed doses may exert important effects on kidney function. Whether this is related to the development of high blood pressure and cardiovascular diseases remains to be further assessed. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 4 | 20% |
Canada | 3 | 15% |
Peru | 2 | 10% |
United Kingdom | 2 | 10% |
Israel | 1 | 5% |
Unknown | 8 | 40% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 11 | 55% |
Practitioners (doctors, other healthcare professionals) | 7 | 35% |
Scientists | 2 | 10% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 1% |
Unknown | 81 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 16 | 20% |
Student > Bachelor | 14 | 17% |
Other | 12 | 15% |
Researcher | 9 | 11% |
Student > Ph. D. Student | 6 | 7% |
Other | 14 | 17% |
Unknown | 11 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 20 | 24% |
Biochemistry, Genetics and Molecular Biology | 13 | 16% |
Nursing and Health Professions | 12 | 15% |
Agricultural and Biological Sciences | 8 | 10% |
Pharmacology, Toxicology and Pharmaceutical Science | 4 | 5% |
Other | 12 | 15% |
Unknown | 13 | 16% |