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TWIST1 associates with NF-κB subunit RELA via carboxyl-terminal WR domain to promote cell autonomous invasion through IL8 production

Overview of attention for article published in BMC Biology, August 2012
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Title
TWIST1 associates with NF-κB subunit RELA via carboxyl-terminal WR domain to promote cell autonomous invasion through IL8 production
Published in
BMC Biology, August 2012
DOI 10.1186/1741-7007-10-73
Pubmed ID
Authors

Shan Li, Stephen E Kendall, Raquel Raices, James Finlay, Maricela Covarrubias, Zheng Liu, Gina Lowe, Yu-Huey Lin, Yuan Han Teh, Victoria Leigh, Simi Dhillon, Steven Flanagan, Karen S Aboody, Carlotta A Glackin

Abstract

Metastasis is the primary cause of death for cancer patients. TWIST1, an evolutionarily conserved basic helix-loop-helix (bHLH) transcription factor, is a strong promoter of metastatic spread and its expression is elevated in many advanced human carcinomas. However, the molecular events triggered by TWIST1 to motivate dissemination of cancer cells are largely unknown.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 30 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 27%
Researcher 4 13%
Professor > Associate Professor 3 10%
Student > Bachelor 2 7%
Professor 1 3%
Other 3 10%
Unknown 9 30%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 23%
Biochemistry, Genetics and Molecular Biology 7 23%
Medicine and Dentistry 3 10%
Veterinary Science and Veterinary Medicine 1 3%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Other 1 3%
Unknown 10 33%