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X Demographics
Mendeley readers
Attention Score in Context
Title |
A series of N-terminal epitope tagged Hdh knock-in alleles expressing normal and mutant huntingtin: their application to understanding the effect of increasing the length of normal huntingtin’s polyglutamine stretch on CAG140 mouse model pathogenesis
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Published in |
Molecular Brain, August 2012
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DOI | 10.1186/1756-6606-5-28 |
Pubmed ID | |
Authors |
Shuqiu Zheng, Nima Ghitani, Jessica S Blackburn, Jeh-Ping Liu, Scott O Zeitlin |
Abstract |
Huntington's disease (HD) is an autosomal dominant neurodegenerative disease that is caused by the expansion of a polyglutamine (polyQ) stretch within Huntingtin (htt), the protein product of the HD gene. Although studies in vitro have suggested that the mutant htt can act in a potentially dominant negative fashion by sequestering wild-type htt into insoluble protein aggregates, the role of the length of the normal htt polyQ stretch, and the adjacent proline-rich region (PRR) in modulating HD mouse model pathogenesis is currently unknown. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 7% |
United Kingdom | 1 | 2% |
Unknown | 37 | 90% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 11 | 27% |
Student > Ph. D. Student | 10 | 24% |
Student > Bachelor | 6 | 15% |
Student > Master | 2 | 5% |
Professor > Associate Professor | 2 | 5% |
Other | 2 | 5% |
Unknown | 8 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 18 | 44% |
Biochemistry, Genetics and Molecular Biology | 6 | 15% |
Neuroscience | 5 | 12% |
Physics and Astronomy | 1 | 2% |
Psychology | 1 | 2% |
Other | 2 | 5% |
Unknown | 8 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 August 2012.
All research outputs
#18,312,024
of 22,673,450 outputs
Outputs from Molecular Brain
#857
of 1,103 outputs
Outputs of similar age
#128,827
of 167,805 outputs
Outputs of similar age from Molecular Brain
#6
of 6 outputs
Altmetric has tracked 22,673,450 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,103 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 167,805 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one.