4⃣ASOはドラべ症候群モデルマウスのけいれん発作を改善する https://t.co/Yem7gQJYw4 未だ治療法のないドラべ症候群に対し、核酸医薬品を用いた治療アプローチの確立を目指した論文です。最先端な創薬の世界へダイブしたい方にピッタリです! #核酸医薬品 #ASO #個別化医療
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RT @Sukant_Khurana: Antisense oligonucleotides increase Scn1a expression and reduce seizures and SUDEP incidence in a mouse model of Dr… ht…
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Antisense oligonucleotides increase Scn1a expression and reduce seizures and SUDEP incidence in a mouse model of Dr… https://t.co/ymBo52QXwk
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@hcmefford: What if we could prevent the poison exon from being spliced into the transcript? Lori Isom and STOKE: Targeted augmentation of nuclear gene output (TANGO). ASO that binds to the poison exon and prevents splicing of the exon. https://t.co/pUj