Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication published as: https://t.co/RT079zAEwt @naturecomms #biorxiv
GC376/373, black market protease inhibitor, for cats Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication https://t.co/IAMNSkNRK6
@biologistimo A “fun” bit of trivia is that Paxlovid was basically borrowed from wild/cats health because of their sensitivity to coronaviruses and prior research which led to the discovery of its prodrug GC376 😺
RT @PicodaMirandola: @boni_castellane @EureosCriss Il paxlovid poteva uscire molto prima. Sono anni che usiamo le proteasi per trattare i c…
RT @PicodaMirandola: @boni_castellane @EureosCriss Il paxlovid poteva uscire molto prima. Sono anni che usiamo le proteasi per trattare i c…
@boni_castellane @EureosCriss Il paxlovid poteva uscire molto prima. Sono anni che usiamo le proteasi per trattare i coronavirus felini. https://t.co/4a9mKuGYV7
“Its "conserved" nature between the different genera/species of Coronavirus reflects its critical role for the viral cycle; and also explains that GC376/373, developed against FCoV Mpro, also works against SARS-CoV-2 Mpro” #antiviral #therapeutics #FCoV #F
RT @C_A_Gustave: 30/79 Sa nature "conservée" entre les différents genres/espèces de Coronavirus traduit son rôle critique pour le cycle vir…
RT @C_A_Gustave: 30/79 Sa nature "conservée" entre les différents genres/espèces de Coronavirus traduit son rôle critique pour le cycle vir…
30/79 Sa nature "conservée" entre les différents genres/espèces de Coronavirus traduit son rôle critique pour le cycle viral ; et explique aussi que le GC376/373, développé contre la Mpro de FCoV, fonctionne aussi contre la Mpro de SARS-CoV-2 https://t.co/
RT @Mujhunter: @Covid19Crusher Nope... not going to pay Merck $700 for a revamped Veterinary Feline FIP drug, while I have my Zinc + EGCG/Q…
@Covid19Crusher Nope... not going to pay Merck $700 for a revamped Veterinary Feline FIP drug, while I have my Zinc + EGCG/Quinine and IVM. Paxovid is an analogue "tweak" of their GC373 drug for Feline FIP. And I'm sure that doesn't cost $700/treatment.
RT @ivanajpavlovic: #FelineInfectiousPeritonitis, a fatal coronavirus infection in cats, was successfully treated previously with a prodrug…
@SuskiFi @HeikkiRay @CyrusQ Testataanko kissojen omaa koronavirusta yleensä? Niitä testejä mainostettiin jokin aika sitten Kiinasta käsin. https://t.co/me95wzJUFA
#FelineInfectiousPeritonitis, a fatal coronavirus infection in cats, was successfully treated previously with a prodrug #GC376, a dipeptide-based #ProteaseInhibitor. The prodrug & its parent #GC373 are effective inhibitors of the #Mpro from both #SARSC
@MichaelTeng88 @EricTopol My understanding as well, in that this was based on GC376/GC373, which has had an underground and ongoing following in the FIPV community. But which was also tested last year in vitro. https://t.co/OvfxdNyHdh
@profLemieux https://t.co/WppaRWIvuB Your work deserves credit as well, for @pfizer's COVID19 3LC protease inhibitor success. https://t.co/li2snqrd9W
RT @tcelltracker: Feline coronavirus drug inhibits #SARSCoV2 protease. Such a cool example of why #comparativeimmunology is important! 🐈 @N…
RT @tcelltracker: Feline coronavirus drug inhibits #SARSCoV2 protease. Such a cool example of why #comparativeimmunology is important! 🐈 @N…
https://t.co/UM5nkvJQaF @wargonm @DocPepper_FR @Le___Doc ... savez-vous si cela est toujours d’actualité ? Question posée ce matin par un patient, je n’ai pas su quoi répondre
@XavierHugonet @DebunkMoutarde https://t.co/UM5nkvJQaF ... et même on vous fournit de quoi botter le cul au virus. Révise le concept One Health ... ça peut faire du bien
RT @DelthiaRicks: In the lab: Antiviral drug for a cat coronavirus infection works against #SARSCoV2. Canadian researchers who made the dis…
@Mazelmind Es decir, el coronavirus del gato tiene baja frecuencia en la población, pero es altamente letal. Por lo que una inmunidad del 50% no es despreciable. Pero qué más hay tras el FcoV?, tratamientos, y hay publicaciones que incorporan esto al SARS-
Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication | Nature Communications @Le___Doc @DocPepper_FR @wargonm ce traitement est très efficace chez le chat,qu’en est-il de l’étude humaine? https://t.co/UM5nkvJ
RT @59Caca: Универзитет у Алберти @UofAResearch научници откривају да је лек који се користи за лечење #coronavirus инфекција код мачака М…
RT @K9FCR: @yoshipatho ネコのコロナFIPの治療薬としてのmain protease inhibitor の1つであるGC376を、新型コロナにも応用できる可能性は、昨年の夏からすでに指摘してきたのですがね…はてさて。
@yoshipatho ネコのコロナFIPの治療薬としてのmain protease inhibitor の1つであるGC376を、新型コロナにも応用できる可能性は、昨年の夏からすでに指摘してきたのですがね…はてさて。
@asahi ようやくですか。レムデシビルとの併用かつ軽症者への早期投与で、重症化が防げる可能性は高いと見ています。
RT @K9FCR: イベルメクチンもmain protease阻害活性が強いとなると、ネコのコロナFIPの治療薬にも使えるかも知れない?! イヌの寄生虫のフィラリア薬が、ネコのコロナウイルス性の致死的疾患に有効だと誰が想像するだろうか? https://t.co/ReS2R…
イベルメクチンもmain protease阻害活性が強いとなると、ネコのコロナFIPの治療薬にも使えるかも知れない?! イヌの寄生虫のフィラリア薬が、ネコのコロナウイルス性の致死的疾患に有効だと誰が想像するだろうか?
@Alzhacker 教えていただきありがとうございます。開発コードNo.が近いので、類似薬かも知れませんね。 元々、ネコのコロナFIPで有効だったレムデシビルを端緒に、前臨床開発中のGCシリーズも、ヒトにも使われて効けば良いなあと思ってました。 そこにイベルメクチンが割って入ってきた感じで少し興奮してます。
Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication https://t.co/fuVN9YYtOv
@MartinaSisters via @BidoliNicola Patent: https://t.co/x3meOjgdM0 Story you know of course: A Much-Hyped COVID-19 Drug Almost Identical to Black-Market Cat Cure https://t.co/HwJWYx7cUy Paper again you know: Feline coronavirus drug inhibits main protease o
RT @flavinkins: They were related to the peptide fragment recognized by the MPro protease of all members of Coronaviridae. The aldehyde gro…
RT @59Caca: Универзитет у Алберти @UofAResearch научници откривају да је лек који се користи за лечење #coronavirus инфекција код мачака М…
RT @Uyulaya: A drug candidate for treatment of Feline Infectious Peritonitis (aka FIP, a fatal condition caused by a #coronavirus in cats)…
A drug candidate for treatment of Feline Infectious Peritonitis (aka FIP, a fatal condition caused by a #coronavirus in cats) seems to show activity against #SARSCoV2 😺 https://t.co/8keaheeepj
Les vétérinaires au secours des humains... Les entendrons nous cette fois ci? J'en dtoute, vacciner la population est plus rentable! https://t.co/fECOqCk98g
RT @SaraGilEdwards1: Quizá tardemos+d lo q pensábamos en obtener vacuna con eficacia probada.Estudios plantean una nueva y esperanzadora lí…
RT @SaraGilEdwards1: Quizá tardemos+d lo q pensábamos en obtener vacuna con eficacia probada.Estudios plantean una nueva y esperanzadora lí…
@fffeeerrr68 @joseukscience Por lo que veo están siguiendo una línea de tratamiento propuesta desde hace años para peritonitis infecciosa felina (producida por otro coronavirus) con inhibidores de la proteasa Mpro (o 3CLpro). https://t.co/NIwmgipZHB
RT @MinaCoen: @TheCoronaKreml1 @wierdduk @Bij88941056 @we_ever_evolve @NOS Als deze discussie over veelbelovende middelen ging, ipv dat men…
@TheCoronaKreml1 @wierdduk @Bij88941056 @we_ever_evolve @NOS Als deze discussie over veelbelovende middelen ging, ipv dat men vasthoudt aan HCQ, dan was het allang over bijv GC373 gegaan. Is ook een veel interessantere discussie om te voeren. https://t.co/
RT @ferrtwee: Qui l'originale su @NatureComms https://t.co/WWKPSPUYdV
Kedi koronavirüs ilacının , SARS-CoV-2'nin ana proteazını inhibe ederek ,virüs replikasyonunu engellediğini gösteren çalışma https://t.co/tQwwtfrBU8
"Claramente, estos medicamentos deben avanzar rápidamente en ensayos en humanos para COVID-19" https://t.co/IReW1NcDhE
An excellent ground work for repurposing feline coronavirus drug for possible treatment of human coronavirus infections... https://t.co/bSY7vfX28w
@neuromanter Ik zag deze nog langskomen over een paar protease inhibitoren: https://t.co/h5ZfUERgMu https://t.co/o1mNDz2vQE (Boceprevir, gebruikt voor behandeling hepatitis C & kat coronavirus drugs GC376 & GC373). Maar nog lange weg te gaan eer di
We >might< have viable COVID-19 drugs! Very long way to go to prove safety and efficacy in humans, but this is very hopeful news. Feline coronavirus drug (GC 373 & GC376) inhibits the main protease of SARS-CoV-2 and blocks virus replication http
An antiviral drug being developed to treat FIP prevented SARS-CoV and #SARSCoV2 from replicating in cell cultures via @nature https://t.co/Dbzs58Jfod #MammalMonday
Qui l'originale su @NatureComms https://t.co/WWKPSPUYdV
Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication. https://t.co/JEB3zrCVKf https://t.co/8mjhRJmpzM
RT @DrDarrenRFlower: #drugs Boceprevir & GC376 inhibit #COVID19 by binding its #protease #Mpro https://t.co/jGzz9jOIfv https://t.co/ac5pUH…
RT @DrDarrenRFlower: #drugs Boceprevir & GC376 inhibit #COVID19 by binding its #protease #Mpro https://t.co/jGzz9jOIfv https://t.co/ac5pUH…
RT @DrDarrenRFlower: #drugs Boceprevir & GC376 inhibit #COVID19 by binding its #protease #Mpro https://t.co/jGzz9jOIfv https://t.co/ac5pUH…
RT @DrDarrenRFlower: #drugs Boceprevir & GC376 inhibit #COVID19 by binding its #protease #Mpro https://t.co/jGzz9jOIfv https://t.co/ac5pUH…
RT @DrDarrenRFlower: #drugs Boceprevir & GC376 inhibit #COVID19 by binding its #protease #Mpro https://t.co/jGzz9jOIfv https://t.co/ac5pUH…
RT @DrDarrenRFlower: #drugs Boceprevir & GC376 inhibit #COVID19 by binding its #protease #Mpro https://t.co/jGzz9jOIfv https://t.co/ac5pUH…
#drugs Boceprevir & GC376 inhibit #COVID19 by binding its #protease #Mpro https://t.co/jGzz9jOIfv https://t.co/ac5pUHjHyi https://t.co/Gq0liOsH8S #HPLovecraft #dccomics #newhaven @anjbth @UbE3Ligase @foxymania @DaveshChauhan11 @jdshastri26 @grawoig @
RT @3dciencia: Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication https://t.co/J3U3ZqRJ2L https:…
Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication. https://t.co/1ttOwgmrtJ
Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication https://t.co/J3U3ZqRJ2L https://t.co/wbyWCCeH4a
Michis
He is the best ! Follow him🙏🏻
I have always been a dog person to be honest
Una droga para tratar la FIP felina podría ser capaz de inhibir la replicación del SARS-COV-2 en humanos. 💊💊💊
RT @ManoloSanchezA: Aquí tenéis otro ejemplo de porqué la experiencia de la investigación #veterinaria en #coronavirus puede ser de gran va…
Aquí tenéis otro ejemplo de porqué la experiencia de la investigación #veterinaria en #coronavirus puede ser de gran valor para luchar contra la actual pandemia. Inhibidores de proteasa de la peritonitis infecciosa felina también inhiben al #SARS-CoV-2 #On
@OlifaNT Is dit niet wat voor ze? GC373/GC376? https://t.co/9AJbV9JY06
RT @GabLamap: Pour une fois que les chats pourraient servir à quelque chose https://t.co/AJ4C4TnPLZ #coronavirus #COVIDー19
Pour une fois que les chats pourraient servir à quelque chose https://t.co/AJ4C4TnPLZ #coronavirus #COVIDー19
RT @lamethodeFC: [L’étude à découvrir] 27/08 > Le médicament contre le #coronavirus félin inhibe la principale protéase du #SARSCoV2 et blo…
RT @lamethodeFC: [L’étude à découvrir] 27/08 > Le médicament contre le #coronavirus félin inhibe la principale protéase du #SARSCoV2 et blo…
[L’étude à découvrir] 27/08 > Le médicament contre le #coronavirus félin inhibe la principale protéase du #SARSCoV2 et bloque la réplication du #virus https://t.co/Hh0YNUo1It via @NatureComms #LaMethSci
RT @thelonevirologi: Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication https://t.co/nGx2ndIJ4F
RT @profLemieux: Our research on the feline drug #GC373 to target SARS-CoV2 main protease is out in @NatureComms Great teamwork at the @Uof…
RT @pcr_wada_com: Nature Communications 8月27日 ネコのコロナウイルス(Feline Coronavirus, FCoV)の薬は、コロナウイルスが作るタンパク質分解酵素の活性を阻害します。 #新型コロナウイルス では、nsp5のキモトリ…
👇Important new work looking at a possible treatment for COVID19. Led by a badass lady scientist - congratulations @profLemieux!
RT @profLemieux: Our research on the feline drug #GC373 to target SARS-CoV2 main protease is out in @NatureComms Great teamwork at the @Uof…
RT @profLemieux: Our research on the feline drug #GC373 to target SARS-CoV2 main protease is out in @NatureComms Great teamwork at the @Uof…
Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication https://t.co/nGx2ndIJ4F
New article by @profLemieux Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication https://t.co/7xaZrrL5HB
RT @pcr_wada_com: Nature Communications 8月27日 ネコのコロナウイルス(Feline Coronavirus, FCoV)の薬は、コロナウイルスが作るタンパク質分解酵素の活性を阻害します。 #新型コロナウイルス では、nsp5のキモトリ…
@erolkbl Tedavi etme konusunda ciddi değiller demek ki. Bu araştırma 1 hafta önce yayınlandı https://t.co/0uUjyPl99h
RT @pcr_wada_com: Nature Communications 8月27日 ネコのコロナウイルス(Feline Coronavirus, FCoV)の薬は、コロナウイルスが作るタンパク質分解酵素の活性を阻害します。 #新型コロナウイルス では、nsp5のキモトリ…
RT @LairmoreDVMDean: Comparative virology in action- Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus repl…
Alright alright 👏🏽👏🏽
👀
RT @catvetsusan: Development of drugs for #FIP in cats has benefitted people in the search for #COVID19 treatments. I do fear that these dr…
Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication https://t.co/k10XbHWSvw
RT @LairmoreDVMDean: Comparative virology in action- Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus repl…