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Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups

Overview of attention for article published in Annals of the Rheumatic Diseases, August 2012
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2 tweeters

Citations

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57 Dimensions

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47 Mendeley
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Title
Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups
Published in
Annals of the Rheumatic Diseases, August 2012
DOI 10.1136/annrheumdis-2012-201851
Pubmed ID
Authors

Kenneth M Kaufman, Jian Zhao, Jennifer A Kelly, Travis Hughes, Adam Adler, Elena Sanchez, Joshua O Ojwang, Carl D Langefeld, Julie T Ziegler, Adrienne H Williams, Mary E Comeau, Miranda C Marion, Stuart B Glenn, Rita M Cantor, Jennifer M Grossman, Bevra H Hahn, Yeong Wook Song, Chack-Yung Yu, Judith A James, Joel M Guthridge, Elizabeth E Brown, Graciela S Alarcón, Robert P Kimberly, Jeffrey C Edberg, Rosalind Ramsey-Goldman, Michelle A Petri, John D Reveille, Luis M Vilá, Juan-Manuel Anaya, Susan A Boackle, Anne M Stevens, Barry I Freedman, Lindsey A Criswell, Joo-Hyun Lee, Ji-Seon Lee, Deh-Ming Chang, R Hal A Scofield, Gary S Gilkeson, Joan T Merrill, Timothy B Niewold, Timothy James Vyse, Sang-Cheol Bae, Chaim O Jacob, Kathy Moser Sivils, Patrick M Gaffney, John B Harley, Amr H Sawalha, Betty P Tsao

Abstract

The Xq28 region containing IRAK1 and MECP2 has been identified as a risk locus for systemic lupus erythematosus (SLE) in previous genetic association studies. However, due to the strong linkage disequilibrium between IRAK1 and MECP2, it remains unclear which gene is affected by the underlying causal variant(s) conferring risk of SLE.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 1 2%
United States 1 2%
Netherlands 1 2%
Colombia 1 2%
Unknown 43 91%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 19%
Researcher 9 19%
Student > Master 8 17%
Student > Bachelor 4 9%
Professor 4 9%
Other 13 28%
Readers by discipline Count As %
Medicine and Dentistry 18 38%
Agricultural and Biological Sciences 12 26%
Biochemistry, Genetics and Molecular Biology 6 13%
Immunology and Microbiology 5 11%
Unspecified 3 6%
Other 3 6%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 August 2012.
All research outputs
#7,755,802
of 12,361,872 outputs
Outputs from Annals of the Rheumatic Diseases
#3,715
of 4,818 outputs
Outputs of similar age
#70,844
of 125,997 outputs
Outputs of similar age from Annals of the Rheumatic Diseases
#51
of 88 outputs
Altmetric has tracked 12,361,872 research outputs across all sources so far. This one is in the 23rd percentile – i.e., 23% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,818 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 14th percentile – i.e., 14% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 125,997 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 88 others from the same source and published within six weeks on either side of this one. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.