RT @AvrahamCooperMD: 4/ In addition to membrane disruption, AmB also induces fungal mitochondrial damage. This leads to reactive oxygen spe…
675 followers
625 followers
RT @AvrahamCooperMD: 4/ In addition to membrane disruption, AmB also induces fungal mitochondrial damage. This leads to reactive oxygen spe…
625 followers
RT @AvrahamCooperMD: 13/ Disrupting cell membranes may play a role in AmB infusion reactions. But it turns out that AmB also binds to some…
115,903 followers
13/ Disrupting cell membranes may play a role in AmB infusion reactions. But it turns out that AmB also binds to some Toll-like Receptors (TLR), which recognize microbial products and jumpstart immune responses. This activates the innate immune system.