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Sequence analysis for detection of first-line drug resistance in Mycobacterium tuberculosis strains from a high-incidence setting

Overview of attention for article published in BMC Microbiology, May 2012
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (70th percentile)
  • Good Attention Score compared to outputs of the same age and source (70th percentile)

Mentioned by

policy
1 policy source
twitter
1 X user

Citations

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78 Dimensions

Readers on

mendeley
130 Mendeley
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Title
Sequence analysis for detection of first-line drug resistance in Mycobacterium tuberculosis strains from a high-incidence setting
Published in
BMC Microbiology, May 2012
DOI 10.1186/1471-2180-12-90
Pubmed ID
Authors

Silke Feuerriegel, Barbara Oberhauser, Abu Garawani George, Foday Dafae, Elvira Richter, Sabine Rüsch-Gerdes, Stefan Niemann

Abstract

Drug resistance displays a problem for the therapy of Mycobacterium tuberculosis infections. For molecular resistance testing, it is essential to have precise knowledge on genomic variations involved in resistance development. However, data from high-incidence settings are only sparely available. Therefore we performed a systematic approach and analyzed a total of 97 M. tuberculosis strains from previously treated patients in Sierra Leone for mutations in katG, rpoB, rrs, rpsL, gidB, embB, pncA and where applicable in inhA and ahpC. Of the strains investigated 50 were either mono- or poly-resistant to isoniazid, rifampin, streptomycin, ethambutol and pyrazinamide or MDR and 47 fully susceptible strains served as controls.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 130 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 2 2%
Unknown 128 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 25 19%
Student > Master 24 18%
Student > Ph. D. Student 22 17%
Professor 11 8%
Student > Postgraduate 7 5%
Other 17 13%
Unknown 24 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 31 24%
Medicine and Dentistry 26 20%
Biochemistry, Genetics and Molecular Biology 21 16%
Immunology and Microbiology 7 5%
Computer Science 6 5%
Other 10 8%
Unknown 29 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 February 2021.
All research outputs
#7,356,343
of 25,374,917 outputs
Outputs from BMC Microbiology
#792
of 3,489 outputs
Outputs of similar age
#49,822
of 178,898 outputs
Outputs of similar age from BMC Microbiology
#11
of 40 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 3,489 research outputs from this source. They receive a mean Attention Score of 4.3. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 178,898 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 40 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.