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Brain activation differences in schizophrenia during context-dependent processing of saccade tasks

Overview of attention for article published in Behavioral and Brain Functions, June 2016
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Title
Brain activation differences in schizophrenia during context-dependent processing of saccade tasks
Published in
Behavioral and Brain Functions, June 2016
DOI 10.1186/s12993-016-0103-2
Pubmed ID
Authors

A. L. Rodrigue, B. P. Austin, K. A. Dyckman, J. E. McDowell

Abstract

Brain function in schizophrenia has been probed using saccade paradigms and functional magnetic resonance imaging, but little information exists about how changing task context impacts saccade related brain activation and behavioral performance. We recruited schizophrenia and comparison subjects to perform saccade tasks in differing contexts: (1) two single task runs (anti- or pro-saccades alternating with fixation) and (2) one dual task run (antisaccades alternating with prosaccades). Context-dependent differences in saccade circuitry were evaluated using ROI analyses. Distinction between anti- and pro-saccade activation across contexts (single versus dual task) suggests that the schizophrenia group did not respond to context in the same way as the comparison group. Further investigation of context processing effects on brain activation and saccade performance measures informs models of cognitive deficits in the disorder and enhances understanding of antisaccades as a potential endophenotype for schizophrenia.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 36 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 6 17%
Student > Ph. D. Student 5 14%
Student > Doctoral Student 4 11%
Researcher 3 8%
Other 2 6%
Other 3 8%
Unknown 13 36%
Readers by discipline Count As %
Neuroscience 7 19%
Psychology 5 14%
Agricultural and Biological Sciences 2 6%
Medicine and Dentistry 2 6%
Nursing and Health Professions 1 3%
Other 4 11%
Unknown 15 42%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 June 2016.
All research outputs
#20,334,427
of 22,879,161 outputs
Outputs from Behavioral and Brain Functions
#332
of 391 outputs
Outputs of similar age
#305,328
of 352,727 outputs
Outputs of similar age from Behavioral and Brain Functions
#3
of 4 outputs
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