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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Genome-wide association study of prolactin levels in blood plasma and cerebrospinal fluid
|
|---|---|
| Published in |
BMC Genomics, June 2016
|
| DOI | 10.1186/s12864-016-2785-0 |
| Pubmed ID | |
| Authors |
Lyndsay A. Staley, Mark T. W. Ebbert, Sheradyn Parker, Matthew Bailey, Perry G. Ridge, Alison M. Goate, John S. K. Kauwe |
| Abstract |
Prolactin is a polypeptide hormone secreted by the anterior pituitary gland that plays an essential role in lactation, tissue growth, and suppressing apoptosis to increase cell survival. Prolactin serves as a key player in many life-critical processes, including immune system and reproduction. Prolactin is also found in multiple fluids throughout the body, including plasma and cerebrospinal fluid (CSF). In this study, we measured prolactin levels in both plasma and CSF, and performed a genome-wide association study. We then performed meta-analyses using METAL with a significance threshold of p < 5 × 10(-8) and removed SNPs where the direction of the effect was different between the two datasets. We identified 12 SNPs associated with increased prolactin levels in both biological fluids. Our efforts will help researchers understand how prolactin is regulated in both CSF and plasma, which could be beneficial in research for the immune system and reproduction. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 25% |
| United Kingdom | 1 | 25% |
| Unknown | 2 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Scientists | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 28 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 6 | 21% |
| Professor | 4 | 14% |
| Other | 3 | 11% |
| Student > Doctoral Student | 2 | 7% |
| Professor > Associate Professor | 2 | 7% |
| Other | 5 | 18% |
| Unknown | 6 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 5 | 18% |
| Neuroscience | 5 | 18% |
| Biochemistry, Genetics and Molecular Biology | 4 | 14% |
| Agricultural and Biological Sciences | 2 | 7% |
| Social Sciences | 1 | 4% |
| Other | 2 | 7% |
| Unknown | 9 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 July 2016.
All research outputs
#2,662,486
of 22,880,230 outputs
Outputs from BMC Genomics
#890
of 10,666 outputs
Outputs of similar age
#49,226
of 352,012 outputs
Outputs of similar age from BMC Genomics
#27
of 226 outputs
Altmetric has tracked 22,880,230 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 10,666 research outputs from this source. They receive a mean Attention Score of 4.7. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 352,012 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 226 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.