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Anti-MDA5-Positive Dermatomyositis Presenting as Fever of Unknown Origin

Overview of attention for article published in JGIM: Journal of General Internal Medicine, June 2016
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2 tweeters

Citations

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16 Mendeley
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Title
Anti-MDA5-Positive Dermatomyositis Presenting as Fever of Unknown Origin
Published in
JGIM: Journal of General Internal Medicine, June 2016
DOI 10.1007/s11606-016-3769-0
Pubmed ID
Authors

Lori W. Lee, Neera S. Narang, Anna Postolova, Nicole Seminara, Molly A. Kantor

Abstract

Dermatomyositis is a chronic systemic autoimmune disease characterized by inflammatory infiltrates in the skin and muscle. The wide variability in clinical and serologic presentation poses a diagnostic challenge for the internist. Appreciation of the clinical variants of dermatomyositis allows for expedient diagnosis and avoidance of diagnostic error. We illustrate these challenges with the case of a 51-year-old Vietnamese-American man who initially presented with fever of unknown origin in the absence of overt skin and muscle manifestations. The diagnosis of dermatomyositis was not evident on several clinical encounters due to the absence of these hallmark symptoms. We review the variable clinical manifestations of a subtype of dermatomyositis associated with an autoantibody against melanoma differentiation-associated protein 5 (anti-MDA5) and suggest consideration of dermatomyositis as a diagnosis in patients presenting with systemic illness and markedly elevated ferritin, even in the absence of elevated muscle enzymes and classic autoantibodies.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 16 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 19%
Other 2 13%
Student > Postgraduate 2 13%
Student > Ph. D. Student 2 13%
Student > Master 1 6%
Other 3 19%
Unknown 3 19%
Readers by discipline Count As %
Medicine and Dentistry 8 50%
Agricultural and Biological Sciences 1 6%
Pharmacology, Toxicology and Pharmaceutical Science 1 6%
Immunology and Microbiology 1 6%
Unspecified 1 6%
Other 1 6%
Unknown 3 19%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 December 2016.
All research outputs
#9,860,899
of 12,348,320 outputs
Outputs from JGIM: Journal of General Internal Medicine
#3,545
of 4,308 outputs
Outputs of similar age
#187,332
of 268,635 outputs
Outputs of similar age from JGIM: Journal of General Internal Medicine
#91
of 142 outputs
Altmetric has tracked 12,348,320 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,308 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.5. This one is in the 7th percentile – i.e., 7% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 268,635 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 142 others from the same source and published within six weeks on either side of this one. This one is in the 7th percentile – i.e., 7% of its contemporaries scored the same or lower than it.