↓ Skip to main content

Mesenchymal Stem Cells

Overview of attention for book
Cover of 'Mesenchymal Stem Cells'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Mesenchymal Stem Cells
  3. Altmetric Badge
    Chapter 2 Bone Tissue Engineering: Past-Present-Future.
  4. Altmetric Badge
    Chapter 3 Mesenchymal Stem Cells for Osteochondral Tissue Engineering.
  5. Altmetric Badge
    Chapter 4 Mesenchymal Stem Cells
  6. Altmetric Badge
    Chapter 5 Mesenchymal Stem Cells
  7. Altmetric Badge
    Chapter 6 Mesenchymal Stem Cells in Lipogems, a Reverse Story: from Clinical Practice to Basic Science.
  8. Altmetric Badge
    Chapter 7 Paracrine Mechanisms of Mesenchymal Stem Cells in Tissue Repair.
  9. Altmetric Badge
    Chapter 8 Mesenchymal Stem Cells
  10. Altmetric Badge
    Chapter 9 Colony Forming Unit Assays.
  11. Altmetric Badge
    Chapter 10 Methods and Strategies for Lineage Tracing of Mesenchymal Progenitor Cells.
  12. Altmetric Badge
    Chapter 11 Mesenchymal Stem Cells
  13. Altmetric Badge
    Chapter 12 Mesenchymal Stem Cells
  14. Altmetric Badge
    Chapter 13 Mesenchymal Stem Cells
  15. Altmetric Badge
    Chapter 14 Mesenchymal Stem Cells
  16. Altmetric Badge
    Chapter 15 Isolation, Expansion, and Immortalization of Human Adipose-Derived Mesenchymal Stromal Cells from Biopsies and Liposuction Specimens.
  17. Altmetric Badge
    Chapter 16 Optimization of Mesenchymal Stem Cells to Increase Their Therapeutic Potential.
  18. Altmetric Badge
    Chapter 17 Mesenchymal Stem Cells
  19. Altmetric Badge
    Chapter 18 Isolation and Manufacture of Clinical-Grade Bone Marrow-Derived Human Mesenchymal Stromal Cells.
  20. Altmetric Badge
    Chapter 19 Quality Control Assays for Clinical-Grade Human Mesenchymal Stromal Cells: Methods for ATMP Release.
  21. Altmetric Badge
    Chapter 20 Quality Control Assays for Clinical-Grade Human Mesenchymal Stromal Cells: Validation Strategy.
  22. Altmetric Badge
    Chapter 21 Mesenchymal Stem Cells
  23. Altmetric Badge
    Chapter 22 Clinical-Grade Manufacturing of Therapeutic Human Mesenchymal Stem/Stromal Cells in Microcarrier-Based Culture Systems.
  24. Altmetric Badge
    Chapter 23 GMP-Compliant Expansion of Clinical-Grade Human Mesenchymal Stromal/Stem Cells Using a Closed Hollow Fiber Bioreactor.
  25. Altmetric Badge
    Chapter 24 Engineering Small-Scale and Scaffold-Based Bone Organs via Endochondral Ossification Using Adult Progenitor Cells.
  26. Altmetric Badge
    Chapter 25 Fabrication of Elasticity-Tunable Gelatinous Gel for Mesenchymal Stem Cell Culture.
  27. Altmetric Badge
    Chapter 26 Mesenchymal Stem Cells
  28. Altmetric Badge
    Chapter 27 Tips on How to Collect and Administer the Mesenchymal Stem Cell Secretome for Central Nervous System Applications.
  29. Altmetric Badge
    Chapter 28 Soluble Factors from Human Fetal Bone Marrow-Derived Mesenchymal Stem Cells: Preparation of Conditioned Medium and Its Effect on Tumor Cells.
  30. Altmetric Badge
    Chapter 29 Mesenchymal Stem Cells
  31. Altmetric Badge
    Chapter 30 Transcriptomic Analysis of Adult Renal Derived Mesenchymal Stem-Like Cells.
  32. Altmetric Badge
    Chapter 31 Proteomic Analysis of Mesenchymal Stem Cells.
  33. Altmetric Badge
    Chapter 32 Unraveling Mesenchymal Stem Cells' Dynamic Secretome Through Nontargeted Proteomics Profiling.
  34. Altmetric Badge
    Chapter 33 Identification of Factors Produced and Secreted by Mesenchymal Stromal Cells with the SILAC Method.
Attention for Chapter 17: Mesenchymal Stem Cells
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (76th percentile)
  • High Attention Score compared to outputs of the same age and source (85th percentile)

Mentioned by

twitter
3 X users
patent
1 patent

Citations

dimensions_citation
21 Dimensions

Readers on

mendeley
56 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Chapter title
Mesenchymal Stem Cells
Chapter number 17
Book title
Mesenchymal Stem Cells
Published in
Methods in molecular biology, January 2016
DOI 10.1007/978-1-4939-3584-0_17
Pubmed ID
Book ISBNs
978-1-4939-3582-6, 978-1-4939-3584-0
Authors

Lian, Qizhou, Zhang, Yuelin, Liang, Xiaoting, Gao, Fei, Tse, Hung-Fat, Qizhou Lian M.D., Ph.D., Yuelin Zhang M.D., Ph.D., Xiaoting Liang M.D., Fei Gao M.D., Hung-Fat Tse M.D., Ph.D., Qizhou Lian, Yuelin Zhang, Xiaoting Liang, Fei Gao, Hung-Fat Tse

Editors

Massimiliano Gnecchi

Abstract

Multipotent stromal cells, also known as mesenchymal stem cells (MSCs), possess great potential to generate a wide range of cell types including endothelial cells, smooth muscle cells, bone, cartilage, and lipid cells. This protocol describes in detail how to perform highly efficient, lineage-specific differentiation of human-induced pluripotent stem cells (iPSCs) with an MSCs fate. The approach uses a clinically compliant protocol with chemically defined media, feeder-free conditions, and a CD105 positive and CD24 negative selection to achieve a single cell-based MSCs derivation from differentiating human pluripotent cells in approximately 20 days. Cells generated with this protocol express typical MSCs surface markers and undergo adipogenesis, osteogenesis, and chondrogenesis similar to adult bone marrow-derived MSCs (BM-MSCs). Nonetheless, compared with adult BM-MSCs, iPSC-MSCs display a higher proliferative capacity, up to 120 passages, without obvious loss of self-renewal potential and constitutively express MSCs surface antigens. MSCs generated with this protocol have numerous applications, including expansion to large scale cell numbers for tissue engineering and the development of cellular therapeutics. This approach has been used to rescue limb ischemia, allergic disorders, and cigarette smoke-induced lung damage and to model mesenchymal and vascular disorders of Hutchinson-Gilford progeria syndrome (HGPS).

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 2%
Sweden 1 2%
Unknown 54 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 14%
Student > Bachelor 7 13%
Student > Doctoral Student 6 11%
Student > Ph. D. Student 6 11%
Student > Master 5 9%
Other 9 16%
Unknown 15 27%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 13 23%
Medicine and Dentistry 7 13%
Agricultural and Biological Sciences 7 13%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Engineering 2 4%
Other 6 11%
Unknown 19 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 April 2020.
All research outputs
#5,667,908
of 22,875,477 outputs
Outputs from Methods in molecular biology
#1,569
of 13,131 outputs
Outputs of similar age
#89,940
of 393,689 outputs
Outputs of similar age from Methods in molecular biology
#206
of 1,471 outputs
Altmetric has tracked 22,875,477 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,131 research outputs from this source. They receive a mean Attention Score of 3.4. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 393,689 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 1,471 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.