Chapter title |
Tips on How to Collect and Administer the Mesenchymal Stem Cell Secretome for Central Nervous System Applications.
|
---|---|
Chapter number | 27 |
Book title |
Mesenchymal Stem Cells
|
Published in |
Methods in molecular biology, January 2016
|
DOI | 10.1007/978-1-4939-3584-0_27 |
Pubmed ID | |
Book ISBNs |
978-1-4939-3582-6, 978-1-4939-3584-0
|
Authors |
F. G. Teixeira, S. C. Serra, A. J. Salgado |
Editors |
Massimiliano Gnecchi |
Abstract |
Human mesenchymal stem cells (hMSCs) have been proposed as possible therapeutic agents for central nervous system (CNS) disorders. Recently, it has been suggested that their effects are mostly mediated through their secretome, which contains a number of neuroregulatory molecules capable of increasing cell proliferation, differentiation, and survival in different physiological conditions. Here, we present an overview of the hMSC secretome as a possible candidate in the creation of new cell-free therapies, demonstrating the process of its collection and route of administration, focusing our attention on their effects in CNS regenerative medicine. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 15 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 6 | 40% |
Student > Master | 3 | 20% |
Researcher | 1 | 7% |
Student > Ph. D. Student | 1 | 7% |
Unknown | 4 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Neuroscience | 4 | 27% |
Agricultural and Biological Sciences | 3 | 20% |
Biochemistry, Genetics and Molecular Biology | 2 | 13% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 7% |
Chemistry | 1 | 7% |
Other | 0 | 0% |
Unknown | 4 | 27% |