Title |
Modeling gene expression using chromatin features in various cellular contexts
|
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Published in |
Genome Biology, September 2012
|
DOI | 10.1186/gb-2012-13-9-r53 |
Pubmed ID | |
Authors |
Xianjun Dong, Melissa C Greven, Anshul Kundaje, Sarah Djebali, James B Brown, Chao Cheng, Thomas R Gingeras, Mark Gerstein, Roderic Guigó, Ewan Birney, Zhiping Weng |
Abstract |
Previous work has demonstrated that chromatin feature levels correlate with gene expression. The ENCODE project enables us to further explore this relationship using an unprecedented volume of data. Expression levels from more than 100,000 promoters were measured using a variety of high-throughput techniques applied to RNA extracted by different protocols from different cellular compartments of several human cell lines. ENCODE also generated the genome-wide mapping of eleven histone marks, one histone variant, and DNase I hypersensitivity sites in seven cell lines. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 75% |
France | 1 | 25% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 50% |
Scientists | 2 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 21 | 4% |
United Kingdom | 17 | 3% |
Germany | 8 | 1% |
Spain | 4 | <1% |
Italy | 3 | <1% |
France | 3 | <1% |
China | 3 | <1% |
Netherlands | 2 | <1% |
Australia | 2 | <1% |
Other | 14 | 2% |
Unknown | 499 | 87% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 175 | 30% |
Researcher | 165 | 29% |
Student > Master | 56 | 10% |
Student > Bachelor | 30 | 5% |
Professor > Associate Professor | 28 | 5% |
Other | 91 | 16% |
Unknown | 31 | 5% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 342 | 59% |
Biochemistry, Genetics and Molecular Biology | 98 | 17% |
Computer Science | 40 | 7% |
Medicine and Dentistry | 16 | 3% |
Neuroscience | 8 | 1% |
Other | 31 | 5% |
Unknown | 41 | 7% |