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Induction of IL-6 and CCL5 (RANTES) in human respiratory epithelial (A549) cells by clinical isolates of respiratory syncytial virus is strain specific

Overview of attention for article published in Virology Journal, September 2012
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  • Good Attention Score compared to outputs of the same age and source (68th percentile)

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3 X users
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1 Facebook page

Citations

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30 Dimensions

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61 Mendeley
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Title
Induction of IL-6 and CCL5 (RANTES) in human respiratory epithelial (A549) cells by clinical isolates of respiratory syncytial virus is strain specific
Published in
Virology Journal, September 2012
DOI 10.1186/1743-422x-9-190
Pubmed ID
Authors

Ruth Levitz, Rachel Wattier, Pamela Phillips, Alexandra Solomon, Jessica Lawler, Isaac Lazar, Carla Weibel, Jeffrey S Kahn

Abstract

Respiratory syncytial virus (RSV) is the major respiratory pathogen of infants and young children. During each seasonal epidemic, multiple strains of both subgroup A and B viruses circulate in the community. Like other RNA viruses, RSV genome replication is prone to errors that results in a heterogeneous population of viral strains some of which may possess differences in virulence. We sought to determine whether clinical isolates of RSV differ in their capacity to induce inflammatory cytokines IL-6 and CCL5 (previously known as RANTES [regulated upon activation, normal T-cell expressed and secreted protein]), which are known to be induced in vitro and in vivo in response to RSV, during infection of A549 cells.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 61 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 2%
Unknown 60 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 18%
Researcher 9 15%
Student > Master 6 10%
Student > Bachelor 5 8%
Professor > Associate Professor 4 7%
Other 9 15%
Unknown 17 28%
Readers by discipline Count As %
Agricultural and Biological Sciences 20 33%
Medicine and Dentistry 8 13%
Biochemistry, Genetics and Molecular Biology 6 10%
Immunology and Microbiology 3 5%
Engineering 2 3%
Other 3 5%
Unknown 19 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 February 2013.
All research outputs
#13,871,657
of 22,678,224 outputs
Outputs from Virology Journal
#1,469
of 3,030 outputs
Outputs of similar age
#95,433
of 168,267 outputs
Outputs of similar age from Virology Journal
#30
of 102 outputs
Altmetric has tracked 22,678,224 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,030 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.5. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 168,267 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 102 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.