Title |
Human rotavirus vaccine Rotarix™ provides protection against diverse circulating rotavirus strains in African infants: a randomized controlled trial
|
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Published in |
BMC Infectious Diseases, September 2012
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DOI | 10.1186/1471-2334-12-213 |
Pubmed ID | |
Authors |
Andrew Duncan Steele, Kathleen M Neuzil, Nigel A Cunliffe, Shabir A Madhi, Pieter Bos, Bagrey Ngwira, Desiree Witte, Stacy Todd, Cheryl Louw, Mari Kirsten, Sanet Aspinall, Leen Jan Van Doorn, Alain Bouckenooghe, Pemmaraju V Suryakiran, Htay Htay Han |
Abstract |
Rotaviruses are the most important cause of severe acute gastroenteritis worldwide in children <5 years of age. The human, G1P[8] rotavirus vaccine Rotarix™ significantly reduced severe rotavirus gastroenteritis episodes in a Phase III clinical trial conducted in infants in South Africa and Malawi. This paper examines rotavirus vaccine efficacy in preventing severe rotavirus gastroenteritis, during infancy, caused by the various G and P rotavirus types encountered during the first rotavirus-season. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 3 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Hungary | 1 | <1% |
United States | 1 | <1% |
Malawi | 1 | <1% |
Brazil | 1 | <1% |
Unknown | 129 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 32 | 24% |
Student > Ph. D. Student | 19 | 14% |
Researcher | 17 | 13% |
Student > Bachelor | 13 | 10% |
Other | 6 | 5% |
Other | 19 | 14% |
Unknown | 27 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 40 | 30% |
Agricultural and Biological Sciences | 17 | 13% |
Immunology and Microbiology | 9 | 7% |
Nursing and Health Professions | 7 | 5% |
Social Sciences | 6 | 5% |
Other | 19 | 14% |
Unknown | 35 | 26% |