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Twitter Demographics
Mendeley readers
Attention Score in Context
| Title |
Polar/Ionizable Residues in Transmembrane Segments: Effects on Helix-Helix Packing
|
|---|---|
| Published in |
PLOS ONE, September 2012
|
| DOI | 10.1371/journal.pone.0044263 |
| Pubmed ID | |
| Authors |
Manuel Bañó-Polo, Carlos Baeza-Delgado, Mar Orzáez, Marc A. Marti-Renom, Concepción Abad, Ismael Mingarro |
| Abstract |
The vast majority of membrane proteins are anchored to biological membranes through hydrophobic α-helices. Sequence analysis of high-resolution membrane protein structures show that ionizable amino acid residues are present in transmembrane (TM) helices, often with a functional and/or structural role. Here, using as scaffold the hydrophobic TM domain of the model membrane protein glycophorin A (GpA), we address the consequences of replacing specific residues by ionizable amino acids on TM helix insertion and packing, both in detergent micelles and in biological membranes. Our findings demonstrate that ionizable residues are stably inserted in hydrophobic environments, and tolerated in the dimerization process when oriented toward the lipid face, emphasizing the complexity of protein-lipid interactions in biological membranes. |
Twitter Demographics
The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 50 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 2% |
| Chile | 1 | 2% |
| France | 1 | 2% |
| India | 1 | 2% |
| Spain | 1 | 2% |
| United States | 1 | 2% |
| Unknown | 44 | 88% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 17 | 34% |
| Researcher | 9 | 18% |
| Professor | 4 | 8% |
| Student > Bachelor | 4 | 8% |
| Student > Doctoral Student | 3 | 6% |
| Other | 11 | 22% |
| Unknown | 2 | 4% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 21 | 42% |
| Agricultural and Biological Sciences | 20 | 40% |
| Chemistry | 5 | 10% |
| Computer Science | 1 | 2% |
| Physics and Astronomy | 1 | 2% |
| Other | 1 | 2% |
| Unknown | 1 | 2% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 September 2012.
All research outputs
#15,251,053
of 22,678,224 outputs
Outputs from PLOS ONE
#129,864
of 193,568 outputs
Outputs of similar age
#106,258
of 168,582 outputs
Outputs of similar age from PLOS ONE
#2,736
of 4,262 outputs
Altmetric has tracked 22,678,224 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 193,568 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 168,582 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 4,262 others from the same source and published within six weeks on either side of this one. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.