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Cancer specific promoter CpG Islands hypermethylation of HOP homeobox (HOPX) gene and its potential tumor suppressive role in pancreatic carcinogenesis

Overview of attention for article published in BMC Cancer, September 2012
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Title
Cancer specific promoter CpG Islands hypermethylation of HOP homeobox (HOPX) gene and its potential tumor suppressive role in pancreatic carcinogenesis
Published in
BMC Cancer, September 2012
DOI 10.1186/1471-2407-12-397
Pubmed ID
Authors

Mina Waraya, Keishi Yamashita, Hiroshi Katoh, Akira Ooki, Hiroshi Kawamata, Hiroshi Nishimiya, Kazunori Nakamura, Akira Ema, Masahiko Watanabe

Abstract

We have recently identified HOP hoemobox (HOPX) as a tumor suppressor gene candidate, characterized by tumor-specific promoter DNA hypermethylation in human cancers, and it can remarkably inhibit tumors' aggressive phenotypes. In this current study, we for the first time examined methylation level of HOPX and tested the functional relevance in pancreatic cancer (PC).

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 3%
United States 1 3%
Brazil 1 3%
Unknown 35 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 34%
Researcher 7 18%
Student > Master 3 8%
Student > Bachelor 2 5%
Other 2 5%
Other 5 13%
Unknown 6 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 10 26%
Medicine and Dentistry 9 24%
Biochemistry, Genetics and Molecular Biology 7 18%
Immunology and Microbiology 2 5%
Psychology 1 3%
Other 1 3%
Unknown 8 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 September 2012.
All research outputs
#14,606,450
of 22,678,224 outputs
Outputs from BMC Cancer
#3,613
of 8,245 outputs
Outputs of similar age
#102,130
of 169,032 outputs
Outputs of similar age from BMC Cancer
#50
of 98 outputs
Altmetric has tracked 22,678,224 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,245 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 55% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 169,032 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 98 others from the same source and published within six weeks on either side of this one. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.