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Increased ratio of anti-apoptotic to pro-apoptotic Bcl2 gene-family members in lithium-responders one month after treatment initiation

Overview of attention for article published in Biology of Mood & Anxiety Disorders, September 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (91st percentile)
  • Above-average Attention Score compared to outputs of the same age and source (60th percentile)

Mentioned by

news
1 news outlet
twitter
3 X users
patent
3 patents

Citations

dimensions_citation
48 Dimensions

Readers on

mendeley
32 Mendeley
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Title
Increased ratio of anti-apoptotic to pro-apoptotic Bcl2 gene-family members in lithium-responders one month after treatment initiation
Published in
Biology of Mood & Anxiety Disorders, September 2012
DOI 10.1186/2045-5380-2-15
Pubmed ID
Authors

Lori Lowthert, Janine Leffert, Aiping Lin, Sheila Umlauf, Kathleen Maloney, Anjana Muralidharan, Boris Lorberg, Shrikant Mane, Hongyu Zhao, Rajita Sinha, Zubin Bhagwagar, Robert Beech

Abstract

Lithium is considered by many as the gold standard medication in the management of bipolar disorder (BD). However, the clinical response to lithium is heterogeneous, and the molecular basis for this difference in response is unknown. In the present study, we sought to determine how the peripheral blood gene expression profiles of patients with bipolar disorder (BD) changed over time following intitiation of treatment with lithium, and whether differences in those profiles over time were related to the clinical response.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 32 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 19%
Researcher 6 19%
Student > Postgraduate 5 16%
Student > Bachelor 3 9%
Other 2 6%
Other 5 16%
Unknown 5 16%
Readers by discipline Count As %
Medicine and Dentistry 8 25%
Agricultural and Biological Sciences 6 19%
Biochemistry, Genetics and Molecular Biology 3 9%
Neuroscience 2 6%
Psychology 1 3%
Other 3 9%
Unknown 9 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 March 2023.
All research outputs
#2,402,184
of 24,452,844 outputs
Outputs from Biology of Mood & Anxiety Disorders
#18
of 66 outputs
Outputs of similar age
#15,345
of 171,600 outputs
Outputs of similar age from Biology of Mood & Anxiety Disorders
#3
of 5 outputs
Altmetric has tracked 24,452,844 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 66 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.1. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 171,600 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.