| Title |
Pathogenesis of tendinopathies: inflammation or degeneration?
|
|---|---|
| Published in |
Arthritis Research & Therapy, June 2009
|
| DOI | 10.1186/ar2723 |
| Pubmed ID | |
| Authors |
Michele Abate, Karin Gravare Silbernagel, Carl Siljeholm, Angelo Di Iorio, Daniele De Amicis, Vincenzo Salini, Suzanne Werner, Roberto Paganelli |
| Abstract |
The intrinsic pathogenetic mechanisms of tendinopathies are largely unknown and whether inflammation or degeneration has the prominent role is still a matter of debate. Assuming that there is a continuum from physiology to pathology, overuse may be considered as the initial disease factor; in this context, microruptures of tendon fibers occur and several molecules are expressed, some of which promote the healing process, while others, including inflammatory cytokines, act as disease mediators. Neural in-growth that accompanies the neovessels explains the occurrence of pain and triggers neurogenic-mediated inflammation. It is conceivable that inflammation and degeneration are not mutually exclusive, but work together in the pathogenesis of tendinopathies. |
X Demographics
The data shown below were collected from the profiles of 70 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 7 | 10% |
| United Kingdom | 7 | 10% |
| United States | 4 | 6% |
| Germany | 2 | 3% |
| Canada | 2 | 3% |
| Brazil | 2 | 3% |
| Netherlands | 1 | 1% |
| Finland | 1 | 1% |
| Italy | 1 | 1% |
| Other | 11 | 16% |
| Unknown | 32 | 46% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 56 | 80% |
| Scientists | 10 | 14% |
| Practitioners (doctors, other healthcare professionals) | 4 | 6% |
Mendeley readers
The data shown below were compiled from readership statistics for 818 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 5 | <1% |
| Brazil | 3 | <1% |
| United States | 2 | <1% |
| Spain | 2 | <1% |
| Austria | 2 | <1% |
| Italy | 2 | <1% |
| Portugal | 1 | <1% |
| Cyprus | 1 | <1% |
| Norway | 1 | <1% |
| Other | 3 | <1% |
| Unknown | 796 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 120 | 15% |
| Student > Bachelor | 120 | 15% |
| Student > Ph. D. Student | 81 | 10% |
| Researcher | 65 | 8% |
| Other | 61 | 7% |
| Other | 169 | 21% |
| Unknown | 202 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 268 | 33% |
| Nursing and Health Professions | 90 | 11% |
| Sports and Recreations | 84 | 10% |
| Agricultural and Biological Sciences | 37 | 5% |
| Engineering | 27 | 3% |
| Other | 74 | 9% |
| Unknown | 238 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 55. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 February 2024.
All research outputs
#793,964
of 25,880,948 outputs
Outputs from Arthritis Research & Therapy
#59
of 3,422 outputs
Outputs of similar age
#2,012
of 123,282 outputs
Outputs of similar age from Arthritis Research & Therapy
#2
of 29 outputs
Altmetric has tracked 25,880,948 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,422 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.3. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 123,282 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 29 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.