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PFA toolbox: a MATLAB tool for Metabolic Flux Analysis

Overview of attention for article published in BMC Systems Biology, July 2016
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Title
PFA toolbox: a MATLAB tool for Metabolic Flux Analysis
Published in
BMC Systems Biology, July 2016
DOI 10.1186/s12918-016-0284-1
Pubmed ID
Authors

Yeimy Morales, Gabriel Bosque, Josep Vehí, Jesús Picó, Francisco Llaneras

Abstract

Metabolic Flux Analysis (MFA) is a methodology that has been successfully applied to estimate metabolic fluxes in living cells. However, traditional frameworks based on this approach have some limitations, particularly when measurements are scarce and imprecise. This is very common in industrial environments. The PFA Toolbox can be used to face those scenarios. Here we present the PFA (Possibilistic Flux Analysis) Toolbox for MATLAB, which simplifies the use of Interval and Possibilistic Metabolic Flux Analysis. The main features of the PFA Toolbox are the following: (a) It provides reliable MFA estimations in scenarios where only a few fluxes can be measured or those available are imprecise. (b) It provides tools to easily plot the results as interval estimates or flux distributions. (c) It is composed of simple functions that MATLAB users can apply in flexible ways. (d) It includes a Graphical User Interface (GUI), which provides a visual representation of the measurements and their uncertainty. (e) It can use stoichiometric models in COBRA format. In addition, the PFA Toolbox includes a User's Guide with a thorough description of its functions and several examples. The PFA Toolbox for MATLAB is a freely available Toolbox that is able to perform Interval and Possibilistic MFA estimations.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 2 4%
Sweden 1 2%
Singapore 1 2%
Unknown 49 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 17 32%
Researcher 9 17%
Student > Doctoral Student 6 11%
Student > Bachelor 4 8%
Librarian 3 6%
Other 11 21%
Unknown 3 6%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 14 26%
Engineering 8 15%
Chemical Engineering 7 13%
Agricultural and Biological Sciences 5 9%
Computer Science 3 6%
Other 11 21%
Unknown 5 9%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 October 2016.
All research outputs
#14,913,296
of 25,371,288 outputs
Outputs from BMC Systems Biology
#469
of 1,132 outputs
Outputs of similar age
#200,318
of 369,993 outputs
Outputs of similar age from BMC Systems Biology
#10
of 27 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,132 research outputs from this source. They receive a mean Attention Score of 3.7. This one has gotten more attention than average, scoring higher than 57% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 369,993 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 62% of its contemporaries.