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Therapy of lupus nephritis: lessons learned from clinical research and daily care of patients

Overview of attention for article published in Arthritis Research & Therapy, January 2012
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Citations

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Readers on

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80 Mendeley
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1 CiteULike
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Title
Therapy of lupus nephritis: lessons learned from clinical research and daily care of patients
Published in
Arthritis Research & Therapy, January 2012
DOI 10.1186/ar3656
Pubmed ID
Authors

Frédéric A Houssiau

Abstract

Despite numerous randomized clinical trials over the last three decades for identifying the optimal treatment option for lupus nephritis, renal involvement still significantly impacts the survival and quality of life of patients with lupus and the search for the ideal immunosuppressive regimen is far from complete. The purpose of this review is to summarize the major recent achievements in the field. More specifically, the following topics will be discussed: intravenous cyclophosphamide versus mycophenolate mofetil (MMF) for induction; azathioprine versus MMF for maintenance; targeted therapies. The review will address clues for optimal global care, such as the need for complete initial evaluation, the importance of patient education, the unmasking of non-compliance to therapy, the reason for an early treatment switch in non-responding patients, the need for prolonged immunosuppression, optimal renal protection, and prevention of cardiovascular disease and other comorbidities.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 80 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 1%
Russia 1 1%
Uruguay 1 1%
Italy 1 1%
Unknown 76 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 14%
Student > Doctoral Student 10 13%
Student > Postgraduate 9 11%
Other 8 10%
Student > Master 7 9%
Other 22 28%
Unknown 13 16%
Readers by discipline Count As %
Medicine and Dentistry 47 59%
Pharmacology, Toxicology and Pharmaceutical Science 4 5%
Nursing and Health Professions 3 4%
Psychology 3 4%
Agricultural and Biological Sciences 2 3%
Other 3 4%
Unknown 18 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 September 2012.
All research outputs
#17,285,036
of 25,371,288 outputs
Outputs from Arthritis Research & Therapy
#2,536
of 3,381 outputs
Outputs of similar age
#172,875
of 253,431 outputs
Outputs of similar age from Arthritis Research & Therapy
#42
of 64 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,381 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one is in the 16th percentile – i.e., 16% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 253,431 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 64 others from the same source and published within six weeks on either side of this one. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.