↓ Skip to main content

Magnesium-free self-assembly of multi-layer DNA objects

Overview of attention for article published in Nature Communications, October 2012
Altmetric Badge

About this Attention Score

  • Average Attention Score compared to outputs of the same age

Mentioned by

twitter
5 X users
facebook
2 Facebook pages

Citations

dimensions_citation
155 Dimensions

Readers on

mendeley
274 Mendeley
citeulike
2 CiteULike
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Magnesium-free self-assembly of multi-layer DNA objects
Published in
Nature Communications, October 2012
DOI 10.1038/ncomms2095
Pubmed ID
Authors

Thomas G. Martin, Hendrik Dietz

Abstract

Molecular self-assembly with DNA offers a route for building user-defined nanoscale objects, but an apparent requirement for magnesium in solution has limited the range of conditions for which practical utility of such objects may be achieved. Here we report conditions for assembling templated multi-layer DNA objects in the presence of monovalent ions, showing that neither divalent cations in general or magnesium in particular are essential ingredients for the successful assembly of such objects. The percentage of DNA strands in an object that do not form thermally stable double-helical DNA domains (T(m)>45 °C) with the template molecule correlated with the sodium requirements for obtaining folded objects. Minimizing the fraction of such weakly binding strands by rational design choices enhanced the yield of folding. The results support the view that DNA-based nanodevices may be designed and produced for a variety of target environments.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 274 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 3 1%
United States 2 <1%
France 1 <1%
Italy 1 <1%
Lithuania 1 <1%
Hungary 1 <1%
Singapore 1 <1%
Germany 1 <1%
Japan 1 <1%
Other 1 <1%
Unknown 261 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 100 36%
Student > Master 42 15%
Researcher 37 14%
Student > Bachelor 33 12%
Student > Doctoral Student 12 4%
Other 15 5%
Unknown 35 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 50 18%
Biochemistry, Genetics and Molecular Biology 44 16%
Physics and Astronomy 43 16%
Chemistry 39 14%
Engineering 29 11%
Other 29 11%
Unknown 40 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 October 2012.
All research outputs
#12,860,995
of 22,679,690 outputs
Outputs from Nature Communications
#37,651
of 46,639 outputs
Outputs of similar age
#89,693
of 172,325 outputs
Outputs of similar age from Nature Communications
#120
of 169 outputs
Altmetric has tracked 22,679,690 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 46,639 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 55.4. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 172,325 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 169 others from the same source and published within six weeks on either side of this one. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.