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Toxoplasma gondii infections among pregnant women, children and HIV-seropositive persons in Accra, Ghana

Overview of attention for article published in Tropical Medicine and Health, June 2016
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Title
Toxoplasma gondii infections among pregnant women, children and HIV-seropositive persons in Accra, Ghana
Published in
Tropical Medicine and Health, June 2016
DOI 10.1186/s41182-016-0018-5
Pubmed ID
Authors

Irene Ayi, Augustine Odoi-Kpoti Sowah, Emmanuel Awusah Blay, Takashi Suzuki, Nobuo Ohta, Patrick F. Ayeh-Kumi

Abstract

Toxoplasma gondii infection can lead to severe disease outcomes in immune-compromised people. This study sought to determine the seroprevalence of anti-T. gondii antibodies among pregnant women, hospitalized children (<5 years old) and HIV-seropositive persons in Accra. A cross-sectional study was conducted in two hospitals in Accra, and a total of 450 voluntary participants were recruited for the study consisting of 125 pregnant women, 200 children and 125 HIV-seropositive persons. Serum was obtained from venous blood safely drawn from each participant and tested for specific anti-Toxoplasma antibodies IgG and IgM by ELISA. A serological criterion for seropositivity was a positive test result for any of the two anti-Toxoplasma antibodies or a combination of both. Questionnaire interviews were conducted to obtain personal information and Toxoplasma infection risk-related data. Those who tested seropositive for anti-T. gondii antibodies were 51.2 % (64/125) pregnant women, 58.0 % (116/200) children and 57.6 % (72/125) HIV patients. The major risk factors associated with anti-T. gondii seropositivity were identified as age (in children), handling raw meat and gravida status (in pregnant women). The results of this study confirmed that the seroprevalence of T. gondii infection is high among pregnant women, hospitalized children <5 years old and HIV patients. A further study to investigate pre-pregnancy infections with T. gondii among women of childbearing age, seroconversion rate in pregnant women, rate of mother-to-child transmission and reactivated infections among HIV-seropositive persons is recommended.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 87 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 87 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 15 17%
Student > Ph. D. Student 12 14%
Researcher 11 13%
Student > Bachelor 9 10%
Student > Postgraduate 5 6%
Other 8 9%
Unknown 27 31%
Readers by discipline Count As %
Medicine and Dentistry 16 18%
Immunology and Microbiology 10 11%
Agricultural and Biological Sciences 9 10%
Biochemistry, Genetics and Molecular Biology 8 9%
Nursing and Health Professions 4 5%
Other 12 14%
Unknown 28 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 July 2016.
All research outputs
#22,759,802
of 25,374,647 outputs
Outputs from Tropical Medicine and Health
#381
of 441 outputs
Outputs of similar age
#309,352
of 353,662 outputs
Outputs of similar age from Tropical Medicine and Health
#7
of 7 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 441 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.9. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 353,662 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one.