↓ Skip to main content

HIV Interactions with Dendritic Cells

Overview of attention for book
Attention for Chapter 2: Antiviral Immune Responses by Human Langerhans Cells and Dendritic Cells in HIV-1 Infection.
Altmetric Badge

About this Attention Score

  • Good Attention Score compared to outputs of the same age (72nd percentile)
  • High Attention Score compared to outputs of the same age and source (82nd percentile)

Mentioned by

wikipedia
1 Wikipedia page

Citations

dimensions_citation
5 Dimensions

Readers on

mendeley
5 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Chapter title
Antiviral Immune Responses by Human Langerhans Cells and Dendritic Cells in HIV-1 Infection.
Chapter number 2
Book title
HIV Interactions with Dendritic Cells
Published in
Advances in experimental medicine and biology, February 2016
DOI 10.1007/978-1-4614-4433-6_2
Pubmed ID
Book ISBNs
978-1-4614-4432-9, 978-1-4614-4433-6
Authors

Linda M. van den Berg, Teunis B. H. Geijtenbeek, van den Berg LM, Geijtenbeek TB

Abstract

The main route of human immunodeficiency virus-1 (HIV-1) infection is via unprotected sexual intercourse, and therefore, vaginal tissues and male foreskin are viral entry sites. Langerhans cells (LCs) and dendritic cells (DCs) are amongst the first immune cells encountering HIV-1 since these cells line these mucosal tissues. Both LCs and DCs are equipped with specific pattern recognition receptors that not only sense pathogens, but induce specific immune responses against these pathogens. LCs express the C-type lectin receptor langerin, which provides protection against HIV-1 infection. In contrast, DCs express the C-type lectin receptor DC-SIGN, which facilitates capture as well as infection of DCs and subsequent transmission to CD4(+) T cells. This chapter gives an update on immune responses elicited against viruses and sheds a light on different immune mechanisms that are hijacked by HIV-1 to infect the host. HIV-1 infection ultimately leads to the worldwide pandemic acquired immunodeficiency syndrome (AIDS).

Mendeley readers

The data shown below were compiled from readership statistics for 5 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 5 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 2 40%
Student > Master 1 20%
Researcher 1 20%
Lecturer 1 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 2 40%
Pharmacology, Toxicology and Pharmaceutical Science 1 20%
Medicine and Dentistry 1 20%
Unknown 1 20%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 March 2013.
All research outputs
#815,928
of 3,632,750 outputs
Outputs from Advances in experimental medicine and biology
#116
of 971 outputs
Outputs of similar age
#24,535
of 94,362 outputs
Outputs of similar age from Advances in experimental medicine and biology
#4
of 47 outputs
Altmetric has tracked 3,632,750 research outputs across all sources so far. This one has received more attention than most of these and is in the 63rd percentile.
So far Altmetric has tracked 971 research outputs from this source. They receive a mean Attention Score of 2.2. This one has gotten more attention than average, scoring higher than 65% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 94,362 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 47 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 82% of its contemporaries.