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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Impact of Percutaneous Revascularization on Exercise Hemodynamics in Patients With Stable Coronary Disease
|
|---|---|
| Published in |
JACC, August 2018
|
| DOI | 10.1016/j.jacc.2018.06.033 |
| Pubmed ID | |
| Authors |
Christopher M. Cook, Yousif Ahmad, James P. Howard, Matthew J. Shun-Shin, Amarjit Sethi, Gerald J. Clesham, Kare H. Tang, Sukhjinder S. Nijjer, Paul A. Kelly, John R. Davies, Iqbal S. Malik, Raffi Kaprielian, Ghada Mikhail, Ricardo Petraco, Firas Al-Janabi, Grigoris V. Karamasis, Shah Mohdnazri, Reto Gamma, Rasha Al-Lamee, Thomas R. Keeble, Jamil Mayet, Sayan Sen, Darrel P. Francis, Justin E. Davies |
| Abstract |
Recently, the therapeutic benefits of percutaneous coronary intervention (PCI) have been challenged in patients with stable coronary artery disease (SCD). The authors examined the impact of PCI on exercise responses in the coronary circulation, the microcirculation, and systemic hemodynamics in patients with SCD. A total of 21 patients (mean age 60.3 ± 8.4 years) with SCD and single-vessel coronary stenosis underwent cardiac catheterization. Pre-PCI, patients exercised on a supine ergometer until rate-limiting angina or exhaustion. Simultaneous trans-stenotic coronary pressure-flow measurements were made throughout exercise. Post-PCI, this process was repeated. Physiological parameters, rate-limiting symptoms, and exercise performance were compared between pre-PCI and post-PCI exercise cycles. PCI reduced ischemia as documented by fractional flow reserve value (pre-PCI 0.59 ± 0.18 to post-PCI 0.91 ± 0.07), instantaneous wave-free ratio value (pre-PCI 0.61 ± 0.27 to post-PCI 0.96 ± 0.05) and coronary flow reserve value (pre-PCI 1.7 ± 0.7 to post-PCI 3.1 ± 1.0; p < 0.001 for all). PCI increased peak-exercise average peak coronary flow velocity (p < 0.0001), coronary perfusion pressure (distal coronary pressure; p < 0.0001), systolic blood pressure (p = 0.01), accelerating wave energy (p < 0.001), and myocardial workload (rate-pressure product; p < 0.01). These changes observed immediately following PCI resulted from the abolition of stenosis resistance (p < 0.0001). PCI was also associated with an immediate improvement in exercise time (+67 s; 95% confidence interval: 31 to 102 s; p < 0.0001) and a reduction in rate-limiting angina symptoms (81% reduction in rate-limiting angina symptoms post-PCI; p < 0.001). In patients with SCD and severe single-vessel stenosis, objective physiological responses to exercise immediately normalize following PCI. This is seen in the coronary circulation, the microcirculation, and systemic hemodynamics. |
X Demographics
The data shown below were collected from the profiles of 133 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 32 | 24% |
| Mexico | 10 | 8% |
| United Kingdom | 9 | 7% |
| Spain | 8 | 6% |
| Venezuela, Bolivarian Republic of | 7 | 5% |
| Turkey | 5 | 4% |
| Brazil | 4 | 3% |
| Argentina | 4 | 3% |
| Australia | 2 | 2% |
| Other | 16 | 12% |
| Unknown | 36 | 27% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 86 | 65% |
| Practitioners (doctors, other healthcare professionals) | 21 | 16% |
| Scientists | 21 | 16% |
| Science communicators (journalists, bloggers, editors) | 5 | 4% |
Mendeley readers
The data shown below were compiled from readership statistics for 68 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 68 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 12 | 18% |
| Researcher | 9 | 13% |
| Student > Bachelor | 5 | 7% |
| Student > Ph. D. Student | 5 | 7% |
| Student > Postgraduate | 5 | 7% |
| Other | 14 | 21% |
| Unknown | 18 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 29 | 43% |
| Nursing and Health Professions | 7 | 10% |
| Engineering | 3 | 4% |
| Sports and Recreations | 3 | 4% |
| Business, Management and Accounting | 1 | 1% |
| Other | 4 | 6% |
| Unknown | 21 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 95. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 September 2019.
All research outputs
#455,035
of 25,729,842 outputs
Outputs from JACC
#1,109
of 16,932 outputs
Outputs of similar age
#9,630
of 342,861 outputs
Outputs of similar age from JACC
#33
of 233 outputs
Altmetric has tracked 25,729,842 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 16,932 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 30.1. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 342,861 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 233 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.