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Mendeley readers
| Title |
A case of Fanconi syndrome accompanied by crystal depositions in tubular cells in a patient with multiple myeloma
|
|---|---|
| Published in |
Kidney Research and Clinical Practice, June 2014
|
| DOI | 10.1016/j.krcp.2014.04.002 |
| Pubmed ID | |
| Authors |
Do Hee Kim, A Young Lim, Hye Bin Gwag, Ji Hyeon Lee, Ki Sun Jung, Keol Lee, Wooseong Huh, Dae Joong Kim, Yoon-Goo Kim, Ha Young Oh, Kihyun Kim, Gee-Young Kwon, Jung Eun Lee |
| Abstract |
Fanconi syndrome (FS) is a rare condition that is characterized by defects in the proximal tubular function. A 48-year-old woman was admitted for evaluation of proteinuria. The patient showed normal anion gap acidosis, normoglycemic glycosuria, hypophosphatemia, and hypouricemia. Thus, her condition was compatible with FS. The M peak was found behind the beta globulin region in urine protein electrophoresis. Upon bone marrow examination, we found that 24% of cells were CD138+ plasma cells with kappa restriction. From a kidney biopsy, we found crystalline inclusions within proximal tubular epithelial cells. Thereafter, she was diagnosed with FS accompanied by multiple myeloma. The patient received chemotherapy and autologous stem cell transplantation, and obtained very good partial hematologic response. However, proximal tubular dysfunction was persistent until 1 year after autologous stem cell transplantation. In short, we report a case of FS accompanied by multiple myeloma, demonstrating crystalline inclusion in proximal tubular cells on kidney biopsy. |
Mendeley readers
The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 38 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 9 | 24% |
| Other | 3 | 8% |
| Professor > Associate Professor | 2 | 5% |
| Researcher | 2 | 5% |
| Professor | 1 | 3% |
| Other | 0 | 0% |
| Unknown | 21 | 55% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 12 | 32% |
| Biochemistry, Genetics and Molecular Biology | 2 | 5% |
| Nursing and Health Professions | 1 | 3% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
| Chemistry | 1 | 3% |
| Other | 1 | 3% |
| Unknown | 20 | 53% |