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MicroRNA-encoded behavior in Drosophila

Overview of attention for article published in Science, October 2015
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (97th percentile)
  • Good Attention Score compared to outputs of the same age and source (77th percentile)

Mentioned by

news
4 news outlets
blogs
4 blogs
twitter
34 X users
googleplus
1 Google+ user

Citations

dimensions_citation
62 Dimensions

Readers on

mendeley
100 Mendeley
citeulike
2 CiteULike
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Title
MicroRNA-encoded behavior in Drosophila
Published in
Science, October 2015
DOI 10.1126/science.aad0217
Pubmed ID
Authors

Joao Picao-Osorio, Jamie Johnston, Matthias Landgraf, Jimena Berni, Claudio R Alonso

Abstract

The relationship between microRNA regulation and the specification of behavior is only beginning to be explored. Here we find that mutation of a single microRNA locus (miR-iab4/8) in Drosophila larvae affects the animal's capacity to correct its orientation if turned upside-down (self-righting). One of the microRNA targets involved in this behavior is the Hox gene Ultrabithorax whose derepression in two metameric neurons leads to self-righting defects. In vivo neural activity analysis reveals that these neurons, the self-righting node (SRN), have different activity patterns in wild type and miRNA mutants while thermogenetic manipulation of SRN activity results in changes in self-righting behavior. Our work thus reveals a microRNA-encoded behavior and suggests that other microRNAs might also be involved in behavioral control in Drosophila and other species.

X Demographics

X Demographics

The data shown below were collected from the profiles of 34 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 100 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
United Kingdom 1 1%
Germany 1 1%
Japan 1 1%
Estonia 1 1%
Unknown 94 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 24 24%
Researcher 13 13%
Student > Bachelor 12 12%
Student > Master 10 10%
Professor 8 8%
Other 18 18%
Unknown 15 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 28 28%
Neuroscience 23 23%
Biochemistry, Genetics and Molecular Biology 22 22%
Medicine and Dentistry 3 3%
Engineering 2 2%
Other 6 6%
Unknown 16 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 79. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 December 2016.
All research outputs
#554,362
of 25,791,949 outputs
Outputs from Science
#12,833
of 83,344 outputs
Outputs of similar age
#8,094
of 295,205 outputs
Outputs of similar age from Science
#314
of 1,373 outputs
Altmetric has tracked 25,791,949 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 83,344 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 66.0. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 295,205 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 1,373 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.