Title |
Genetic Control of Canine Leishmaniasis: Genome-Wide Association Study and Genomic Selection Analysis
|
---|---|
Published in |
PLOS ONE, April 2012
|
DOI | 10.1371/journal.pone.0035349 |
Pubmed ID | |
Authors |
Javier Quilez, Verónica Martínez, John A. Woolliams, Armand Sanchez, Ricardo Pong-Wong, Lorna J. Kennedy, Rupert J. Quinnell, William E. R. Ollier, Xavier Roura, Lluís Ferrer, Laura Altet, Olga Francino |
Abstract |
The current disease model for leishmaniasis suggests that only a proportion of infected individuals develop clinical disease, while others are asymptomatically infected due to immune control of infection. The factors that determine whether individuals progress to clinical disease following Leishmania infection are unclear, although previous studies suggest a role for host genetics. Our hypothesis was that canine leishmaniasis is a complex disease with multiple loci responsible for the progression of the disease from Leishmania infection. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 50% |
Australia | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 1% |
Unknown | 77 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 16 | 21% |
Student > Ph. D. Student | 15 | 19% |
Student > Master | 10 | 13% |
Student > Doctoral Student | 7 | 9% |
Student > Bachelor | 6 | 8% |
Other | 11 | 14% |
Unknown | 13 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 27 | 35% |
Veterinary Science and Veterinary Medicine | 17 | 22% |
Medicine and Dentistry | 7 | 9% |
Biochemistry, Genetics and Molecular Biology | 6 | 8% |
Nursing and Health Professions | 2 | 3% |
Other | 4 | 5% |
Unknown | 15 | 19% |