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Effect of aldosterone on the amplification of oncolytic vaccinia virus in human cancer lines

Overview of attention for article published in Clinical and Molecular Hepatology, September 2011
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Title
Effect of aldosterone on the amplification of oncolytic vaccinia virus in human cancer lines
Published in
Clinical and Molecular Hepatology, September 2011
DOI 10.3350/kjhep.2011.17.3.213
Pubmed ID
Authors

Hyun Ju Lee, Jasung Rho, Shao Ran Gui, Mi Kyung Kim, Yu Kyoung Lee, Yeon Sook Lee, Jeong Eun Kim, Euna Cho, Mong Cho, Tae-Ho Hwang

Abstract

JX-594 is an oncolytic virus derived from the Wyeth vaccinia strain that causes replication-dependent cytolysis and antitumor immunity. Starting with a cross-examination of clinical-trial samples from advanced hepatocellular carcinoma patients having high levels of aldosterone and virus amplification in JX-594 treatment, we investigated the association between virus amplification and aldosterone in human cancer cell lines.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Korea, Republic of 1 4%
Unknown 23 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 38%
Student > Ph. D. Student 3 13%
Student > Master 2 8%
Student > Bachelor 1 4%
Other 1 4%
Other 2 8%
Unknown 6 25%
Readers by discipline Count As %
Agricultural and Biological Sciences 6 25%
Medicine and Dentistry 5 21%
Biochemistry, Genetics and Molecular Biology 4 17%
Immunology and Microbiology 1 4%
Engineering 1 4%
Other 0 0%
Unknown 7 29%